Introduction What Do We Want From an Antiarrhythmic Agent?

Meinertz, T.
March 1988
Angiology;Mar1988 Part 2, Vol. 39, p279
Academic Journal
Focuses on the importance of drugs that are both highly effective against premature depolarizations and are able to prevent sustained ventricular tachycardia and ventricular fibrillation. Examination of the effectiveness and toxicity of antiarrhythmics; Consideration of the limited effectiveness of drugs in the prevention of ventricular tachycardia and ventricular fibrillation; Importance of the side effects of drugs such as the impairment of the contractile machinery of the heart.


Related Articles

  • Dofetilide.  // Reactions Weekly;8/9/2008, Issue 1214, p14 

    The article describes the case of a 62-year-old patient with an implantable cardioverter defibrillator (ICD) who received dofetilide and developed ventricular tachyarrhythmias and ICD-induced ventricular fibrillation. The man was admitted to the hospital after developing syncope and repeated...

  • Cibenzoline overdose.  // Reactions Weekly;2/14/2009, Issue 1239, p9 

    The article describes the case of a woman with chronic kidney disease who developed a myathenia-like syndrome during treatment with cibenzoline for ventricular fibrillation. A clinical history of the patient is discussed, as well as the management of the condition. The patient outcome and a...

  • Pilsicainide.  // Reactions Weekly;3/18/2006, Issue 1093, p28 

    Discusses research being done on pilsicainide induced brugada syndrome. Reference to a study by K. Terajima et al in the January 2006 issue of "Anesthesia and Analgesia"; Medical history of the patient; Electrocardiograph results following pilsicainide administration.

  • Azimilide, A Novel Oral Class III Antiarrhythmic for Both Supraventricular and Ventricular Arrhythmias. VerNooy, Robert A.; Mangrum, J. Michael // Current Drug Targets - Cardiovascular & Haematological Disorders;Feb2005, Vol. 5 Issue 1, p75 

    Azimilide is an investigational Class III antiarrhythmic that has been developed for treating both supraventricular and ventricular tachyarrhythmias. Similar to other Class III antiarrhythmics, azimilide prolongs myocardial repolarization in a dose-dependent manner by increasing the action...

  • Propafenone.  // Reactions Weekly;3/15/2008, Issue 1193, p24 

    The article describes the case of Brugada-like electrocardiography (ECG) changes induced by propafenone administration which was mistaken as acute myocardial infarction. It references a study by S. Chutani and colleagues, published in the February 2008 issue of "Emergency Medicine Journal." A...

  • Sotalol: Current Status and Expanding Indications. Singh, Bramah N. // Journal of Cardiovascular Pharmacology & Therapeutics;Mar1999, Vol. 4 Issue 1, p49 

    The article examines the current status and the expanding indications of the use of antiarrhythmic drug sotalol. It says that the drug can be used in the management of ventricular tachycardia (VT) and ventricular fibrillation (VF) often in conjunction with an implantable...

  • Treatment of ventricular arrhythmias in the elderly. Aronow, Wilbert S. // Geriatrics;Aug2008, Vol. 63 Issue 8, p20 

    Underlying causes of ventricular tachycardia (VT) or complex ventricular arrhythmias (VA) should be treated if possible. Antiarrhythmic drugs should not be used to treat asymptomatic persons with complex VA and no heart disease. Beta blockers are the only antiarrhythmic drugs that have been...

  • Amiodarone: an effective antiarrhythmic drug with unusual side effects. van Erven, Lieselot; Schalij, Martin J. // Heart;Oct2010, Vol. 96 Issue 19, p1593 

    The article discusses the effectiveness and adverse effects of antiarrhythmic drug, amiodarone. Introduced in the early 1960s, amiodarone was initially used for the treatment of angina pectoris. Later, amidarone became a widely used III antiarrhythmic agent. The drug is rich in iodine with...

  • diltiazem.  // Davis's Drug Guide for Nurses, 9th edition;2005, p308 

    Provides information on antiarrhythmic drug diltiazem. Therapeutic use; Pharmacokinetic actions; Side effects; Dosage; Effectiveness.


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics