TITLE

Pathogenesis of Atherosclerosis: I: Role of the Nervous System

AUTHOR(S)
Yao Jun-shen; Wang Jia-fti; Li Hong-ying; Liu Tong-mei; Wu Giang; Duan Wen-zhuo
PUB. DATE
August 1988
SOURCE
Angiology;Aug1988, Vol. 39 Issue 8, p714
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
The new method of lateral carotid artery original-location autograft was used in the present study. An animal model was prepared with which to investigate the neurogenic role in the pathogenesis of atherosclerosis. Two experiments were performed in 16 operated rabbits to whom was fed a cholesterol-rich diet for four months. In the first experiment, the expected results were obtained in 9 rabbits. Significant atherosclerotic plaques were observed in 4 of 9 (44.4%) samples of intact carotid artery; lipid deposition was found in another 3 (33.3%) samples in which atherosclerotic plaques were not observed by the naked eye but were exhibited by light microscopy; negative results were shown only in 2 (22.2%) samples both by the naked eye and by light microscopy. However, atherosclerotic plaques were found only in autograft anastomoses but not within the segment of carotid artery autograft. Then, a second experiment as performed with 7 operated rabbits, and similar results were obtained. These results clearly indicate that the nervous system plays a very important role in the pathogenesis of atherosclerosis.
ACCESSION #
16474770

 

Related Articles

  • Chlamydia pneumoniae in Atherosclerotic Carotid Artery Plaques: High Prevalence among Heavy Smokers. Dobrilovic, Nick; Wright, Creighton B.; Vadlamani, Lou; Meyer, Mark // American Surgeon;Jun2001, Vol. 67 Issue 6, p589 

    This study was designed to determine the prevalence of Chlamydia pneumoniae in carotid artery plaques. Although there have been numerous studies evaluating coronary plaques for this bacterium fewer studies have assessed noncoronary vasculature. In addition we wished to evaluate whether...

  • Electron Microscopic Luminal Surface Characteristics of Carotid Plaques. Kasirajan, Karthikeshwar; Cornu-Labat, Gaston; Turner, John J.; Rubin, Jeffrey R. // Vascular Surgery;Nov/Dec1997, Vol. 31 Issue 6, p769 

    Luminal surface characteristics in symptomatic and asymptomatic patients with carotid artery disease have not been thoroughly evaluated. Carotid artery atherosclerotic plaques were subjected to a scanning electron microscopic (EM) examination to determine plaque surface morphology. Correlation...

  • Lamellar Bone Formation in an Atherosclerotic Plaque of the Carotid Artery, with a Review of Histogenesis. Pauli, Steven; Lauwers, Patrick; van Schil, Paul; Hendriks, Jeroen; van den Brande, Filip; Bogers, John-Paul; van Marck, Erik; Eyskens, Erik // Angiology;Jan2000, Vol. 51 Issue 1, p77 

    Longer existing atherosclerotic lesions may contain calcifications; lamellar bone rarely develops within them. A 59-year-old man was referred with a progressive stroke. A highgrade stenosis of the left common carotid artery, formed by an ulcerating atherosclerotic plaque with a free-floating...

  • IMT Measurement Of Common Carotid Artery Usingmodifiedsnake Contour Segmentation. Dhanalakshmi, S.; Saranya, B.; Sasirekha, M.; Venkatesh, C. // International Journal of Scientific & Technology Research;Jul2013, Vol. 2 Issue 7, p103 

    A new method of segmentation of ultrasound Carotid Artery (CA) has been proposed. Atherosclerosis is the thickening and narrowing of the arteries due to formation of plaque on the walls of the artery. It is one of the major causes of stroke.Intima-media thickness (IMT) is now being considered as...

  • Short-term Tracking of Atherosclerosis in Operated and Unoperated Human Carotid Arteries by High Resolution Magnetic Resonance Imaging. Martin, Kirt; Brownfield, Douglas; Karmonik, Christof; Sanford, Lee; Torres, Lynne; Insull, William; Morrisett, Joel // World Journal of Surgery;Apr2007, Vol. 31 Issue 4, p723 

    A previous study demonstrated the efficacy of a phospholipid (PL) complexed with a protein (apoAI Milano) in causing 4.6% regression of atheroma volume as assessed by intravascular ultrasonography (IVUS) in a group of 47 patients with carotid atherosclerosis. The results of this study raised the...

  • The diameters of common carotid artery and its branches in newborns. Şehirli, Ümit; Yalin, A.; Tulay, C. M.; Cakmak, Y. O.; Gürdal, E. // Surgical & Radiologic Anatomy;Nov2005, Vol. 27 Issue 4, p292 

    The common carotid artery (CCA) bifurcation is of clinical importance due to its vascular access site for intravascular intervention. Additionally, it is also one of the most common sites of atherosclerotic plaque formation. There are numerous studies on the diameters of CCA, internal carotid...

  • Being under strain increases risk of carotid plaques.  // Nursing Standard;5/18/2005, Vol. 19 Issue 36, p19 

    Reports on research on the relationship between psychological strain and carotid atherosclerosis in a general population. Prevalence of atherosclerotic plaques in the carotid arteries; Assessment of psychological strain.

  • Twins Lead to the Prevention of Atherosclerosis: Preliminary Findings of International Twin Study 2009. Tarnoki, Adam Domonkos; Tarnoki, David Laszlo; Stazi, Maria Antonietta; Medda, Emanuela; Cotichini, Rodolfo; Lucatelli, Pierleone; Boatta, Emanuele; Zini, Chiara; Baracchini, Claudio; Meneghetti, Giorgio; Nisticó, Lorenza; Fagnani, Corrado; Fanelli, Fabrizio; Giannoni, Maria Fabrizia; Gazzetti, Marianna; Osztovits, Janos; Jermendy, Gyorgy; Préda, István; Kiss, Róbert Gábor; Littvay, Levente // Journal for Vascular Ultrasound;Jun2011, Vol. 35 Issue 2, p61 

    Introduction.—Atherosclerosis is an inflammatory process in which the artery wall thickens as a result of plaque deposition, but this process may be preceded by increased arterial stiffness. We sought to evaluate the influence of genetics and shared and unshared environmental components...

  • Reconstruction and functional analysis of altered molecular pathways in human atherosclerotic arteries. Cagnin, Stefano; Biscuola, Michele; Patuzzo, Cristina; Trabetti, Elisabetta; Pasquali, Alessandra; Laveder, Paolo; Faggian, Giuseppe; Iafrancesco, Mauro; Mazzucco, Alessandro; Pignatti, Pier Franco; Lanfranchi, Gerolamo // BMC Genomics;2009, Vol. 10, Special section p1 

    Background: Atherosclerosis affects aorta, coronary, carotid, and iliac arteries most frequently than any other body vessel. There may be common molecular pathways sustaining this process. Plaque presence and diffusion is revealed by circulating factors that can mediate systemic reaction leading...

Share

Read the Article

Courtesy of VIRGINIA BEACH PUBLIC LIBRARY AND SYSTEM

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics