A Pilot Study of Iron Depletion as Adjuvant Therapy in Chronic Hepatitis C Patients Not Responding to Interferon

Guyader, Dominique; Boucher, Eveline; André, Patrice; Even, Christian; Cottereau, Jean; Bianchi, Alain; Gasser, Patrick; Mendler, Michel H.; Deugnier, Yves; Brissot, Pierre
June 1999
American Journal of Gastroenterology;Jun1999, Vol. 94 Issue 6, p1696
Academic Journal
The aim of this study was to assess the efficacy of iron depletion obtained by phlebotomy to enhance interferon response in 11 patients who had failed to respond to a standard 3-month interferon treatment. Despite a significant effect on serum aminotransferase levels, there was no effect on viremia, and iron depletion was unable to trigger interferon response.


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