TITLE

A NEW APPROACH TO THE TREATMENT OF ISCHEMIC CONDITIONS OF THE EXTREMITIES: CONTINUOUS INTRAARTERIAL INFUSION THERAPY

AUTHOR(S)
Skalkeas, G.; Balas, P.; Katsogianis, A.; Bakoulas, G.; Karagianakos, R.
PUB. DATE
March 1969
SOURCE
Angiology;Mar1969, Vol. 20 Issue 3, p144
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
A continuous intraarterial infusion therapy has been applied in 36 cases comprising 40 extremities with severe ischemia due to chronic arterial occlusive disease, acute arterial occlusion, after arterial injury, etc. This method consisted of intraarterial infusion of low-molecular-weight dextran (Rheomacrodex) with or without Complamin, a vasodilator drug, through a plastic catheter which was inserted transcutaneously into the main artery of the extremity, i.e., the femoral or brachial artery. The infusion lasted 5 or more days. An evaluation of the arterial circulation of the involved extremity was made prior to, during and after treatment on the basis of careful clinical examination, plethysmography and estimation of the skin temperature of the foot. The early and late results of this therapy are analyzed. A transient improvement of the circulation in ischemic extremities was observed in most of our cases but in the long follow-up period from 1 month to 2 years the salvage of the extremity or the permanent and stable improvement of circulation was observed only in cases which presented an improvement of the collateral circulation, as well as an ability of ischemic tissue to recover from the ischemic changes. This method of treatment can be considered as an extremity salvage procedure in cases of severe ischemia of the extremities or in cases of arterial injury, with borderline circulation, especially if reconstructive arterial surgery cannot be applied or a a supplementary therapy in the ischemic conditions of the extremity, before or after lumbar sympathectomy.
ACCESSION #
16440439

 

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