Zweifach, Benjamin W.
October 1961
Angiology;Oct1961, Vol. 12 Issue 10, p507
Academic Journal
The above observations have focused attention on three important attributes of vascular endothelium: (1) Existence of a variable state of cell tone which not only differs in particular parts of the body, but can be altered by physiologic and pathologic conditions. This type of cell tone is apparently not a reflection of what might be considered as a contractile property of endothelium. (2) Endothelium possesses the property of phagocytizing colloidal materials which becomes increasingly evident under abnormal circumstances. There is no clear-cut evidence relating this phenomenon to that of endothelial vesiculation as described by electron microscopy. (3) The endothelial cell is not a fixed component of the vessel wall but can migrate from its normal position either into the blood stream or into the immediate perivascular space. This can occur without interfering with the functional integrity of the vessel wall.


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