Griep, Arthur H.
September 1963
Angiology;Sep1963, Vol. 14 Issue 9, p484
Academic Journal
1. Fifty patients with angina pectoris caused by various forms of ischemic heart disease received long-term oral therapy with dipyridamole in doses of 25 mg. t.i.d. or q.i.d. 2. Results at the end of a 6-month period of therapy revealed: 80 per cent (40 patients) improved; 20 per cent (10 patients) experienced complete relief; 60 per cent (30 patients) showed moderate to marked improvement of angina pectoris; 14 per cent (7 patients) died as a result of their cardiovascular disease; 6 per cent (3 patients) remained unimproved or had to discontinue therapy. 3. In most angina pectoris patients on long-term oral dipyridamole therapy, relief came slowly and was usually maximal after 3 to 6 months of continuous treatment. 4. No important side effects were encountered as a result of long-term oral administration of dipyridamole. 5. Dipyridamole is a useful drug in the long-term management of the patient with angina pectoris.


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