Captopril for the Treatment of Patients with Hypertension and Peripheral Vascular Disease

Catalano, M.; Libretti, A.
May 1985
Angiology;May1985, Vol. 36 Issue 5, p293
Academic Journal
Many epidemiological studies have shown up the frequent association of areterial hypertension (HT) with atherosclerosis of different localizations. Howe ever, many of the drugs used to treat HT are contraindicated in patients with peripheral vascular disease (PVD), because they cause unfavorable metabolic changes or vasoconstriction. The aim of the present study was to assess the effect of a proven hypotensive drug, captopril, on the peripheral circulation. The drug appeared to be effective in improving blood flow to lower limbs, prolonging the pain. Free interval and increasing the angle/arm arteral pressure index.


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