TITLE

IDIOPATHIC LYMPHEDEMA TREATMENT WITH ADRENAL STEROIDS

AUTHOR(S)
Vainder, Milton
PUB. DATE
October 1963
SOURCE
Angiology;Oct1963, Vol. 14 Issue 10, p524
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
It has been shown that edema fluid provides an excellent media for the proliferation of fibroblasts. In patients in whom edema has been long standing (irrespective of the etiology�but provided it was on a local basis) the results of previous forms of therapy have been legs rewarding than in cases of more recent onset. The beneficial effects of steroid therapy could then be postudated on an interference in fibroblastic activity. It is to be noted in case 1 that the previously described hirsutism did not regress on steroid therapy. This would tend to indicate that the hirsutism is hereditary rather than due to a disturbance in the feed-back mechanism affecting the overproduction of a masculinizing hormone. The findings of normal urinary steroid excretion initially and during the earlier phase of treatment would aim tend to indicate that the favorable response was not brought about through a correction via tile endocrine axis per se. The thought that there may have been improvement due to a non-specific anti-inflammatory effect of steroids was mitigated by the absence of any physical or laboratory findings suggesting inflammation and the immediate relapse and remission when therapy was discontinued and then restarted.
ACCESSION #
16432752

 

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