Fenn, John E.
January 1969
Angiology;Jan1969, Vol. 20 Issue 1, p33
Academic Journal
Statements regarding the Osier's node as a pathognomonic sign of subacute bacte-rial endocarditis still abound in the medical literature. Although it is true that the mucocutaneous lesions, such as Osier's nodes, Janeway's spots, conjunctival pete-chiae and splinter hemorrhages, are more frequently seen in patients with subacute bacterial endocarditis than with other conditions, none are pathognomonic for this disease. Osier's nodes have been described in cases of typhoid fever, gonorrhea, acute bacterial endocarditis, "marantic" endocarditis and systemic lupus erythema-tosus. The Janeway lesion has been recently described in a patient with a mycotic aneurysm." Subungual splinter hemorrhages may be found in 10 to 66 per cent of persons in whom no type of infection can be found and are, therefore, of considerably less diagnostic significance. This paper reports the unusual manifestation of recurrent, classic Osier's nodes in a patient with subacute systemic lupus erythe-matosus who has had no evidence of bacterial endocarditis. The Osier's nodes were intermittently present for more than 2 years. In addition, it would appear that this is the greatest number of Osier's nodes reported in any individual patient as well as the longest duration of recurrent nodes in a patient thus far reported in the medical litera-ture.


Related Articles

  • Acitretin.  // Reactions Weekly;1/21/2006, Issue 1085, p6 

    The article cites a case report on the development of skin and mucosal blistering, eczema, angular cheilitis and rectal bleeding in a 60-year-old woman during treatment with acitretin for discoid lupus erythematosus. It offers information on the commencement of the woman's treatment with...

  • Infective endocarditis complicating rituximab (anti-CD20 monoclonal antibody) treatment in an SLE patient with a past history of Libman-Sacks endocarditis: a case for antibiotic prophylaxis? Armstrong, David; Wright, Stephen; McVeigh, Claire; Finch, Michael // Clinical Rheumatology;Aug2006, Vol. 25 Issue 4, p583 

    We report a 54 year old female whose successful treatment of cerebral lupus with rituximab was complicated by the development of streptococcus intermedius, on valves damaged by Libman-Sacks endocarditis more than 20 years previously.

  • Measurement of damage in 210 Mexican patients with systemic lupus erythematosus: relationship with disease duration. Zonana-Nacach, A.; Camargo-Coronel, A.; Yáñez, P.; de Lourdes Sánchez, M.; Jímenez-Balderas, F.J.; Aceves-Avila, J.; Martínez-Osuna, P.; Fuentes, J.; Medina, F.; Fraga, A. // Lupus;1998, Vol. 7 Issue 2, p119 

    The Systemic Lupus International Collaborating Clinics/American College of Rheumatology (SLICC/ACR) Damage Index is a validated instrument specifically designed to ascertain damage in SLE; this instrument has been applied mainly to Caucasians and African-American SLE patients. The objective of...

  • Silica-induced lupus erythematosus. Haustein, Uwe-Frithjof // Acta Dermato-Venereologica;4/20/98, Vol. 78 Issue 1, p73 

    Describes a case of silica-induced lupus erythematosus. Case background; Action of silica as an adjuvant which increases the immune answer to foreign antigens; Hypergammaglobulinemia.

  • Subacute cutaneous lupus erythematosus: Two cases of delayed diagnosis. Lyon, C. C.; Blewitt, R.; Harrison, P. V. // Acta Dermato-Venereologica;4/20/98, Vol. 78 Issue 1, p57 

    Two cases of subacute cutaneous lupus erythematosus are described. Features which delayed diagnosis are discussed. The potential clinical and histopathological overlap between this condition and erythema multiforme is emphasized, drawing attention to the histological features which allow...

  • Oral lupus erythematosus successfully treated with CO2 laser: a case report. Zoccali, G; Orsini, G; Cifone, MG; Giuliani, M // Lupus;Jul2014, Vol. 23 Issue 8, p848 

    A letter to the editor is presented commenting on oral lupus erythematosus being successfully treated with carbon dioxide laser.

  • Scarred face. Stadler, Franz; Gaspari, Anthony A. // Cortlandt Forum;11/25/99, Vol. 12 Issue 11, p48 

    Examines a case of a 35-year-old male patient with chronic cutaneous lupus erythematosus. Disease manifestations; Laboratory results; Diagnosis; Etiology of the disease.

  • CNS Lupus–Where Do We Go From Here? Isenberg, D.A.; Liang, M.H. // Lupus;1999, Vol. 8 Issue 1, p1 

    Focuses on lupus erythematosus (SLE) disease. Neurological features that are considered part of SLE under the revised American College of Rheumatology citeria; Examples of the imaging techniques used in the investigation of neuropsychiatric lupus; Uses of the standard nomenclature for the...

  • Imiquimod.  // Reactions Weekly;8/13/2011, Issue 1364, p26 

    The article describes two cases of elderly patients who developed lupus erythematosus-like skin reactions while receiving treatment with imiquimod for skin disorders.


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics