Mangieri, C. N.; Cain, R. A.
April 1961
Angiology;Apr1961, Vol. 12 Issue 4, p136
Academic Journal
1. A standardized method is described for determining the lipemia-clearing activity of sublingually administered heparin in experimental animals. 2. Sublingual administration of heparin potassium produces an eightfold increase in plasma lipemia-clearing activity, essentially equivalent to that produced when the drug is given intravenously. 3. The activation of clearing factor upon sublingual administration occurred without alterations in clotting time.


Related Articles

  • Lipid-mediated delivery of brain-specific angiogenesis inhibitor 1 gene reduces corneal neovascularization in an in vivo rabbit model. Yoon, K. C.; Ahn, K. Y.; Lee, J. H.; Chun, B. J.; Park, S. W.; Seo, M. S.; Park, Y.-G.; Kim, K. K. // Gene Therapy;Apr2005, Vol. 12 Issue 7, p617 

    Corneal neovascularization, which occurs in many pathologic states of the cornea, reduces the visual acuity. Recently, we found that the extracellular region of brain-specific angiogenesis inhibitor 1 (BAI1-ECR) has antiproliferative activity through functional blocking ofavß5 integrin in...

  • Ocular Penetration of Linezolid After Oral Administration in Rabbits. Saleh, Maher; Lefevre, Sophie; Bourcier, Tristan; Prevost, Gilles; Gaucher, David; Speeg-Schatz, Claude; Jehl, François // Journal of Ocular Pharmacology & Therapeutics;Jun2011, Vol. 27 Issue 3, p243 

    Purpose: The pharmacokinetics of linezolid (LZD) was investigated in rabbit eyes after single and multiple oral administrations. Setting: Pharmacology Laboratory, University Hospital of Strasbourg, Strasbourg, France. Methods: Twelve New Zealand rabbits were divided into 2 groups: an oral dose...

  • Influence of a probiotic soy product on fecal microbiota and its association with cardiovascular risk factors in an animal model.  // Lipids in Health & Disease;2011, Vol. 10 Issue 1, p126 

    The article cites a research study that analyzes the possible association between fecal microbiota, serum lipid parameters and atherosclerotic lesion development in rabbits with induced hypercholesterolemia. It characterized the fecal microbiota and the rabbits were randomly allocated to five...

  • Intravitreal injection of methotrexate in an experimental rabbit model: Determination of pharmacokinetics. Ozkan, Ebru Bener; Ozcan, Altan A.; Alparslan, Nazan // Indian Journal of Ophthalmology;May2011, Vol. 59 Issue 3, p197 

    Purpose: To investigate the pharmacokinetics of intravitreally administered methotrexate. Materials and Methods: Twenty-one New Zealand white rabbits were used in the study. The pharmacokinetics of intravitreally injected 800 μg/0.1 ml of methotrexate was investigated. Intravitreal...

  • The rabbit gingival tissue response to retraction liquids and tetrahydrozoline. Kostić, Ivan; Mihailović, Dragan; Najman, Stevo; Stojanović, Sanja; Kostić, Milena // Vojnosanitetski Pregled: Military Medical & Pharmaceutical Journ;Jan2014, Vol. 71 Issue 1, p46 

    Backround/Aim. Retraction agents for temporary vertical and lateral suppression of gingival tissue as well as bleeding control and fluid flow in the gingival sulcus are expected to have maximal efficiency without irreversible damage of local tissue and adverse systemic effects. The research...

  • The Effect of Total Bacterial DNA as Co-adjuvant for in vivo Antibody Production. Kazemi, Bahram; Khalili-Tehrani, Sanaz; Bandehpour, Mojgan; Seyed, Negar; Mosaffa, Nariman // Research Journal of Microbiology;2007, Vol. 2 Issue 8, p650 

    In the present research, bacterial DNA of pathogenic Escherichia coli was used as co-adjuvant; sheep blood total immunoglobulin G (IgG) was used as the antigen and complete Freund's adjuvant (CFA) was the adjuvant. Rabbits were injected subcutaneously in the muscle with sheep blood total IgG...

  • Does the concomitant intra-arterial injection of asialoerythropoietin and edaravone mitigate ischaemic mucosal damage after acute superior mesenteric artery thromboembolism in a rabbit autologous fibrin clot model? Sonoda, A.; Nitta, N.; Seko, A.; Ohta, S.; Takemura, S.; Sugimoto, T.; Uzu, T.; Yokomaku, Y.; Takahashi, M.; Kashiwagi, A.; Murata, K. // British Journal of Radiology;Feb2010, Vol. 83 Issue 986, p129 

    To increase the survival rate of patients with acute superior mesenteric artery thromboembolism (ASMAT) treated by catheter thrombolysis, we examined the effects of delivering edaravone and asialoerythropoietin, agents with tissue-protective activities, using a rabbit autologous fibrin clot...

  • A REVIEW ON SELF MICROEMULSIFYING DRUG DELIVERY SYSTEM. Vilas, Pathak Chirag; Gujarathi, Nayan A.; Rane, Bhushan R.; Pawar, Sunil P. // Pharma Science Monitor;Jan2013, Vol. 4 Issue 1, p3628 

    Oral route is one of the most patient friendly routes for the most of the pharmacologically chronic disease treatment. Nearly 40% of new drug candidates exhibit low water solubility and hence high intra- and inter-subject variability and lack of dose proportionality. Much attention has been...

  • Plasma Concentration of Fluconazole After a Single Oral Dose and Administration in Drinking Water in Cockatiels (Nymphicus hollandicus). Ratzlaff, Katherine; Papich, Mark G.; Flammer, Keven // Journal of Avian Medicine & Surgery;Mar2011, Vol. 25 Issue 1, p23 

    Candidiasis frequently affects the oropharynx, esophagus, and crop of juvenile birds with immature immune systems and adult birds that have received long-term antibiotic treatment. Fluconazole is used extensively in human medicine to treat mucosal and invasive candidiasis and has been used in...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics