Effects of Neurosurgical Management of Parkinson's Disease on Speech Characteristics and Oromotor Function

Farrell, Anna; Theodoros, Deborah; Ward, Elizabeth; Hall, Bruce; Silburn, Peter
February 2005
Journal of Speech, Language & Hearing Research;Feb2005, Vol. 48 Issue 1, p5
Academic Journal
The present study examined the effects of neurosurgical management of Parkinson's disease (PD), including the procedures of pallidotomy, thalamotomy, and deep-brain stimulation (DBS) on perceptual speech characteristics, speech intelligibility, and oromotor function in a group of 22 participants with PD. The surgical participant group was compared with a group of 25 non-neurologically impaired individuals matched for age and sex. In addition, the study investigated 16 participants with PD who did not undergo neurosurgical management to control for disease progression. Results revealed that neurosurgical intervention did not significantly change the surgical participants' perceptual speech dimensions or oromotor function despite significant postoperative improvements in ratings of general motor function and disease severity. Reasons why neurosurgical intervention resulted in dissimilar outcomes with respect to participants' perceptual speech dimensions and general motor function are proposed.


Related Articles

  • Subthalamic nucleus stimulation in tremor dominant parkinsonian patients with previous thalamic surgery. Fraix, V.; Pollak, P.; Moro, E.; Chabardes, S.; Xie, J.; Ardouin, C.; Benabid, A. L. // Journal of Neurology, Neurosurgery & Psychiatry;Feb2005, Vol. 76 Issue 2, p246 

    Before of introduction of high frequency stimulation of the subthalamic nucleus (STN), many disabled tremor dominant parkinsonian patients underwent lesioning or chronic electrical stimulation of the thalamus. We studied the effects of STN stimulation in patients with previous ventral...

  • Gamma knife radiosurgery for essential tremor: A Case report and review of the literature. Elaimy, Ameer L.; Demakas, John J.; Arthurs, Benjamin J.; Cooke, Barton S.; Fairbanks, Robert K.; Lamoreaux, Wayne T.; Mackay, Alexander R.; Greeley, David R.; Lee, Christopher M. // World Journal of Surgical Oncology;2010, Vol. 8, p20 

    Approximately 5 million people in America are affected by essential tremors (ET), which are classified as a type of benign movement disorder. This disease manifests as tremors that usually occur in the hands, but they may also be present in the head, face, tongue, and lower limbs. Radiofrequency...

  • Evidence that ventrolateral thalamotomy may eliminate the supraspinal component of both pathological and physiological tremors. Duval, Christian; Panisset, Michel; Bertrand, Gilles; Sadikot, Abbas F. // Experimental Brain Research;May2000, Vol. 132 Issue 2, p216 

    Ventrolateral (VL) thalamotomy produced a marked reduction of oscillations related to the supraspinal components of Parkinson's disease tremor (4�7 Hz) and physiological tremor (8�12 Hz). Finger tremor was examined in nine patients undergoing unilateral VL thalamotomy and in nine...

  • Dynamics of the Subthalamo-pallidal Complex in Parkinson�s Disease During Deep Brain Stimulation. Modolo, J.; Henry, J.; Beuter, A. // Journal of Biological Physics;Jul2008, Vol. 34 Issue 3/4, p351 

    The dynamics of the subthalamo-pallidal complex in Parkinson�s disease during deep brain stimulation (DBS) were studied using two models, a simple firing-rate model and a population-based model. We extended the simple firing-rate model of the complex formed by the subthalamic nucleus (STN)...

  • Nonmotor Symptoms in PD after Deep Brain Stimulation of the Subthalamic Nucleus. Piboolnurak, Panida // Neurology Alert;Jan2008, Vol. 26 Issue 5, p39 

    ALTHOUGH MOTOR SYMPTOMS CONSTITUTE THE CARDINAL features of Parkinson's disease (PD), non-motor symptoms, including neuropsychiatric conditions (depression, anxiety, psychosis, and cognitive impairment), autonomic disorders (orthostatic hypotension, urinary dysfunction, and gastrointestinal...

  • Physiological identification of the human pedunculopontine nucleus. S A Shimamoto // Journal of Neurology, Neurosurgery & Psychiatry;Jan2010, Vol. 81 Issue 1, p80 

    BACKGROUND: The pedunculopontine nucleus (PPN) is a brainstem structure with widespread connections to the basal ganglia. Despite the recent introduction of PPN deep brain stimulation (DBS) for the treatment of gait disorders, little is known about its physiology in humans. METHODS: Single unit...

  • Bilateral subthalamic nucleus stimulation improves balance control in Parkinson's disease. Colnat-Coulbois, S.; Gauchard, G. C.; Maillard, I.; Barroche, G.; Vespignani, H.; Auque, J.; Perrin, Ph. P. // Journal of Neurology, Neurosurgery & Psychiatry;Jun2005, Vol. 76 Issue 6, p780 

    Background: Parkinson's disease (PD), the most common basal ganglia degenerative disease, affects balance control, especially when patients change balance strategy during postural tasks. Bilateral chronic stimulation of the subthalamic nucleus (STN) is therapeutically useful in advanced PD, and...

  • Semantic and affective priming as a function of stimulation of the subthalamic nucleus in Parkinsons disease. Joanna E. Castner; Helen J. Chenery; David A. Copland; Terry J. Coyne; Felicity Sinclair; Peter A. Silburn // Brain: A Journal of Neurology;May2007, Vol. 130 Issue 5, p1395 

    Lexical-semantic and emotional processing deficits have been associated with Parkinsons disease. This study investigated automatic and controlled lexical-semantic processing, the automatic activation of emotional evaluations, and the processing of words conveying negative and neutral emotional...

  • DEEP BRAIN STIMULATION FOR PATIENTS WITH ADVANCED PARKINSONS'S DISEASE. Lau Puay Ngoh; Louis Tan Chew Seng // Singapore Nursing Journal;Jan-Mar2006, Vol. 33 Issue 1, p47 

    Patients with advanced Parkinson's disease (PD) may experience swings in their movement control from periods of normal motor functions to periods of complete immobility. Levodopa remains the gold standard of treatment for Parkinson's disease. However, treatment with levodopa leads to troublesome...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics