Br�nemark, Per-Ingvar
July 1961
Angiology;Jul1961, Vol. 12 Issue 7, p293
Academic Journal
A review is given of various experimental methods used for the study of the vascular architecture and flow pattern of bone marrow. A new method is described, which has been used for the study of the capillary circulation of the fibular marrow of the rabbit. Recent modifications of the method are described, as well as a method for determination of corpuscular flow velocity in the microscope. The architecture and flow pattern of the capillary bed of living, intact bone marrow, as seen under the microscope, is described. Some fundamental problems in bone marrow microcirculation and function are discussed: the function of the sinusoid, intramedullary pressure, open or closed circulation, hemoclastic activity of the sinusoids, relation between bone and mara row circulation, innervation of bone marrow, and influence of changes in the suspension stablity of blood.


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