Virtama, P.; Jänkälä, E.
August 1961
Angiology;Aug1961, Vol. 12 Issue 8, p372
Academic Journal
The effect of serotonin on the renal arteries down to the radiating cortical arterioles was examined by injecting this agent through a polyethylene catheter into the aorta just above the origins of the renal arteries. Radiographic contrast mass (Dionoasil aqueous) was injected immediately after completing the injection of serotonin, and in many cases both agents were injected simultaneously as a mixture. In arteriograms made during and after the injection, signs of arterial constriction were demonstrable neither in the guinea pigs and rabbits, which had been injected with a large single dose of reserpine 24 hours before the examination, nor in the control material. Thus, the authors failed to show any renal arterial response to serotonin.


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