TITLE

UROKINASE -- AN ACTIVATOR OF PLASMINOGEN FROM HUMAN URINE

AUTHOR(S)
Hansen, Per From; Jørgensen, Mogens; Kjeldgaard, Niels Ole; Ploug, Jørgen
PUB. DATE
August 1961
SOURCE
Angiology;Aug1961, Vol. 12 Issue 8, p367
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
It is possible to give urokinase intravascularly, even in large doses, without major side effects. These injections are seen to give rise to a strong fibrinolytic activity in the blood, In the dogs an afibrinogenemia sometimes was observed. Parenchymatous bleedings were never seen with the doses given, neither in men or in dogs. No clear cut therapeutic effect could be demonstrated except in patients with superficial thrombophlebitis, in whom a transient improvement was seen.
ACCESSION #
16429464

 

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