Use of Intravenous Nitroglycerin in the Coronary Care Unit

Cody, Robert
May 1982
Angiology;May1982, Vol. 33 Issue 5, p313
Academic Journal
This article focuses on the use of intravenous nitroglycerin in the coronary care unit. Nitroglycerin is well established as the cornerstone of therapy for angina pectoris resulting from coronary artery disease. In recent years, a large body of data has accumulated indicating the beneficial effects of nitroglycerin in the setting of acute myocardial infarction, congestive heart failure and coronary artery spasm. Studies were performed in hospitalized patients at the New York Hospital-Cornell University Medical Center after their informed consent was obtained. Patients with unstable angina were studied in the coronary care unit, and intravenous nitroglycerin was administered for this indication. Likewise, patients with congestive heart failure were studied in the coronary care unit setting during electrocardiographic and hemodynamic monitoring. The exact mechanism of action for nitroglycerin is unclear. However, it is a smooth-muscle relaxant whose effect on the vascular smooth muscle is predominantly venodilatation.


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