Chazan, Bernard I.
August 1963
Angiology;Aug1963, Vol. 14 Issue 8, p426
Academic Journal
The degree of intra-arteriolar red cell aggregation (RCA) was compared with the chylomicron count and various other indices in 22 recently diagnosed diabetics, and in 48 diabetics who had been under treatment for a 5- to 20-year period. A positive correlation was found in both groups between the degree of RCA and the chylomicron count. RCA was slightly more common in long-established diabetics (62.5 per cent) than in recently diagnosed diabetics (54.6 per cent). On the other hand hyperchylomicronemia was much more common in the �recent� group (81.8 per cent as against 60.5 per cent) than in the �old� group. Significant hyperchylomicronemia (>150 per high power field) was not found in the absence of RCA. Nine of the 12 long-treated diabetics over the age of 65 years had marked hyperchylomicronemia without hypercholesterolemia. A raised erythrocyte sedimentation rate was found in 3 of the �old� group and in 4 of the �recent� group without RCA, but generally the greater the RCA the more common was the incidence of a raised erythrocyte sedimentation rate. Microaneurysms were more commonly found in long-standing diabetes, especially in the presence of RCA. It is concluded that the chylomicron count and RCA, being measures of the particulate content of the plasma, are valuable indices of vascular disease in diabetes.


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