Behar, Solomon; Neufeld, Henry N.
August 1977
Angiology;Aug1977, Vol. 28 Issue 8, p528
Academic Journal
Propranolol and exercise tests were compared for the evaluation of nonspecific ST and T wave changes of the electrocardiogram (ECG). One hundred and fifteen subjects were tested. Forty-six patients with definite ischemic heart disease served as controls (group A), and 69 patients with nonspecific ST-T changes for evaluation (group B). The latter group was divided into two subgroups according to clinical history. Group B-l consisted of 40 subjects with no clinical history of heart disease, and group B-II consisted of 29 patients with a doubtful diagnosis of coronary insufficiency. N 0 patients in the control group reverted to normal ECG patterns after propranolol administration. Among 15 patients of this group who also performed an ergometric test. 13 exhibited typical ST depression of coronary insufficiency. In most subjects of B-l group, the ECG reverted lo a normal pattern after propranotol, but only 55% also had a negative exercise test. Among The doubtful cases (group B-II), there was a poor correlation between the two tests. This study confirms the good correlation between the clinical diagnosis and the propranolol test in the evaluation of atypical repolarization changes of the ECG. However the correlation between the propranolol and exercise tests for this purpose is not conclusive. The propranolol test seems to be very valuable in the assessment and follow-up of patients with nonspecific ST-T changes of the electrocardiogram.


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