Relationship between the Radioisotope Test Using 131I--labelled Serum Albumin and Plethysmographic Blood Flow Measurements in the Study of the Circulation in the Foot

Cuypers, Y.; Steels, P.
November 1981
Angiology;Nov1981, Vol. 32 Issue 11, p742
Academic Journal
A radioisotope test using 131I-labelled serum albumin and venous occlusion plethysmography were performed simultaneously on the feet of normal individuals and patients with peripheral arterial disease during a period of reactive hyperemia. The radioisotope test includes a circulation time and a build-up curve reflecting a local clearance process which is characterized by the parameter M/2 -- delay. Between the parameter M/2 -- delay of the radioisotope test and the blood flow measured by the plethysmograph, the power relationship was found to be: M/2 -- delay = 74.01 F-0.74 with r = 0.69. The experimental data show that the plethysmographic blood flow measurement is an accurate method for the assessment of the peripheral circulation in normal individuals but is less suitable in patients with peripheral arterial disease. The radioisotope test appears to be more valuable than the plethysmographic blood flow measurement for the differentiation of normal individuals from patients with peripheral arterial disease and for the evaluation of the grade of ischemia.


Related Articles

  • Accuracy of plethysmographic indices as predictors of fluid responsiveness in mechanically ventilated adults: a systematic review and meta-analysis. Sandroni, Claudio; Cavallaro, Fabio; Marano, Cristina; Falcone, Chiara; Santis, Paolo; Antonelli, Massimo // Intensive Care Medicine;Sep2012, Vol. 38 Issue 9, p1429 

    Purpose: To systematically review the accuracy of the variation in pulse oxymetry plethysmographic waveform amplitude (∆POP) and the Pleth Variability Index (PVI) as predictors of fluid responsiveness in mechanically ventilated adults. Methods: MEDLINE, Scopus and the Cochrane Database of...

  • Pharmacologic Vasodilation. Spáčil, J.; Linhart, J. // Angiology;Apr1980, Vol. 31 Issue 4, p254 

    The article discusses a clinical case of pharmacologic vasodilation. Prolonged measurement of foot blood flow with the mechanical plethysmograph filled with air or water may be inconvenient to some patients. Since the present study required flow measurements over a period of 4 hours, it was...

  • HSA.  // Taber's Cyclopedic Medical Dictionary (2009);2009, Issue 21, p1096 

    An encyclopedia entry for the medical acronym "HSA," which stands for human serum albumin, is presented.

  • Measuring blood flow.  // British Medical Journal;11/27/1976, Vol. 2 Issue 6047, p1279 

    Focuses on the improvement of methods for blood flow measurement for the understanding of circulatory hemodynamics. Collaboration between medical engineers and clinicians; Application of electronics to medicine; Use of electrical impedance plethysmography for the measurement of blood flow.

  • Blood Flow Changes in the Trapezius Muscle and Overlying Skin Following Transcutaneous Electrical Nerve Stimulation. Sandberg, Margareta L.; Sandberg, Matilda K.; Dahl, Johanna // Physical Therapy;Aug2007, Vol. 87 Issue 8, p1047 

    Background and Purpose Various researchers have studied the effects of transcutaneous electrical nerve stimulation (TENS) on hemodynamics. The purpose of this study was to examine the effects of TENS on local blood flow in the trapezius muscle and overlying skin. Subjects. Thirty-three women who...

  • Analysis of plethysmographic waveform changes induced by beach chair positioning under general anesthesia. Zhu, Richard; Atteya, Gourg; Shelley, Kirk; Silverman, David; Alian, Aymen // Journal of Clinical Monitoring & Computing;Dec2014, Vol. 28 Issue 6, p591 

    During shoulder surgery, patients typically are placed in the beach chair position. In rare cases, this positioning has resulted in devastating outcomes of postoperative cerebral ischemia (Cullen and Kirby in APSF Newsl 22(2):25-27, ; Munis in APSF Newsl 22(4):82-83, ). This study presents a...

  • VASCULAR EFFECTS OF DIHYDROGENATED ERGOT ALKALOIDS. Ulrich, J.; Siggaard-Andersen, J. // Angiology;Dec1971, Vol. 22 Issue 11, p622 

    The effect of dihydroergostine, DE 145 (Sandoz), and dihydroergotamine. DHE, on the blood flow and the capacitance vessels was examined in a comparative, quantitative study, carried out on the right calf of 14 normal adults by aid of plethysmography. The two drugs elicited dissimilar responses...

  • Compliance and reactivity of the peripheral venous system in chronic intermittent hemodialysis. Kooman, Jeroen P.; Wijnen, Jef A. G.; Draaijer, Petra; Van Bortel, Luc M. A. B.; Gladziwa, Ulrich; Peltenburg, Henricus G.; Struyker-Boulder, Harry A. J.; Van Hooff, Johannes P.; Leunissen, Karel M. L. // Kidney International;Apr1992, Vol. 41 Issue 4, p1041 

    A reduced venous compliance and/or inadequate venoconstriction could impair hemodynamics during hemodialysis. Therefore, compliance and reactivity of the peripheral venous system were assessed in hemodialysis patients and controls using strain gauge plethysmography. Reactivity of the venous...


    The dynamic elastic properties and vascular reactions of human blood vessels in vivo are studied by means of the photoplethysmographic method. The measurement of the mechanical properties of the blood vessel walls is based on measurement of blood volume changes resulting from changes in external...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics