Effect of Age, Cardiovascular Disease, and Vasomotor Changes on Transmission of Arterial Pressure Waves Through the Lower Extremities

Carter, Stefan A.
August 1978
Angiology;Aug1978, Vol. 29 Issue 8, p601
Academic Journal
Pressure waves were recorded by indwelling needles in the femoral and foot arteries. At the foot the systolic and pulse pressures were greater and the dicrotic wave more prominent. These changes during transmission increased during vasoconstriction and decreased during vasodilatation. The ratio of the distal to femoral pulse pressure (amplification) increased from 1.13 ± 0.05 during body heating to 1.47 ± 0.06 during body cooling (P < 0.01), and from 1.14 ± 0.10 during infusion of trimethaphan to 1.42 ± 0.02 during cooling (P < 0.05). Amplification was also significantly greater following inhalation of amyl nitrite and during and after Valsalva maneuver. Greater pulse pressure at the foot paralleled greater amplitude of individual harmonics. Phase velocities decreased with increasing frequency and tended to level off at a value similar to the foot-to-foot pulse wave velocity. The findings are consistent with peripheral reflections of the waves which increase during vasoconstriction. In the absence of procedures that elicit vasoconstriction or vasodilatation, amplification averaged 1.35 ± 0.03 in control subjects less than 35 years of age, and 1.24 ± 0.06 in older subjects (P>0.05). Amplification also did not differ significantly between control subjects and patients with hypertension or ischemic heart disease. In the absence of pronounced vasodilatation or encroachment on the lumen by atherosclerotic plaques, systolic and pulse pressures at the foot should be higher than in proximal pulses. These findings provide a firm basis for interpreting measurements of distal systolic pressures by using blood pressure cuffs when examining patients with occlusive arterial disease in the extremities.


Related Articles

  • Prescribing Update. Mead, Mike // Update;9/24/2004, Vol. 69 Issue 4, p118 

    This article presents information related to the treatment of hypertension. To prevent cardiovascular disease, the people should aim for full 24-hour control of a patient's blood pressure (BP), yet this is often not achieved. Maintaining only 18 hours of control leaves the patient exposed to 6...

  • Best use of home BP monitoring.  // Internal Medicine Alert;6/29/2010 Supplement, p96 

    The article reports that home blood pressure (BP) monitoring (HBPM) is a better predictor of cardiovascular (CV) risk that the BP in office.

  • Lifetime CVD risk tied to blood pressure changes at age 55.  // Medical Economics;2/10/2012, Vol. 89 Issue 3, p86 

    The article presents information on a study, according to which increases or decreases in blood pressure in middle age may be associated with higher and lower remaining lifetime risk (LTR) for cardiovascular disease (CVD), coronary heart disease (CHD), and stroke.

  • Body Fat Measured by a Near-Infrared Interactance Device as a Predictor of Cardiovascular Events: The FINRISK'92 Cohort. Pajunen, Pia; Jousilahti, Pekka; Borodulin, Katja; Harald, Kennet; Tuomilehto, Jaakko; Salomaa, Veikko // Obesity (19307381);Apr2011, Vol. 19 Issue 4, p848 

    We evaluated how body fat percentage, measured by a portable near-infrared interactance (NIR) device predicts cardiovascular (CVD), coronary heart disease (CHD), and ischemic stroke events in a prospective population-based survey. The study population consisted of 2,842 men and 3,196 women, who...

  • A LONGITUDINAL STUDY OF BLOOD PRESSURE. Borhani, Nemat O.; Hechter, H. H. // Angiology;Dec1964, Vol. 15 Issue 12, p545 

    1. The results of a longitudinal study of blood pressure among San Francisco longshoremen examined in 1951 and 1961 are presented. 2. Grouping the individuals according to their 1951 systolic and diastotic blood pressure readings, and associating them with mortality from coronary heart disease...

  • Aggressive Blood Pressure Control Increases Coronary Heart Disease Risk Among Diabetic Patients. WENHUI ZHAO; KATZMARZYK, PETER T.; HORSWELL, RONALD; YUJIE WANG; WEI LI; JOHNSON, JOLENE; HEYMSFIELD, STEVEN B.; CEFALU, WILLIAM T.; RYAN, DONNA H.; GANG HU // Diabetes Care;Oct2013, Vol. 36 Issue 10, p3287 

    OBJECTIVE--Blood pressure control can reduce the risk of coronary heart disease (CHD) among diabetic patients; however, it is not known whether the lowest risk of CHD is among diabetic patients with the lowest blood pressure level. RESEARCH DESIGN AND METHODS--We performed a prospective cohort...

  • Arterial Elastance and Wave Reflection Augmentation of Systolic Blood Pressure: Deleterious Effects and Implications for Therapy. Nichols, Wilmer W.; Edwards, David G. // Journal of Cardiovascular Pharmacology & Therapeutics;Jan2001, Vol. 6 Issue 1, p5 

    The article reports that systolic and pulse blood pressures are stronger predictors of stroke, coronary heart disease, myocardial infarction, heart failure, end-stage renal disease, and cardiovascular mortality. Increased elastance of the central elastic arteries is the primary cause of...

  • Antihypertensive Treatment Alters the Predictive Strength of Pulse Pressure and Other Blood Pressure Measures. Greenberg, James // American Journal of Hypertension;Aug2005, Vol. 18 Issue 8, p1033 

    Background: The objective of this study was to assess whether antihypertensive treatment affects the predictive power of brachial pulse pressure. Methods: Data from the First National Health and Nutrition Examination Survey Epidemiologic Follow Up Study were used to conduct Cox regression...

  • ROADMAP and ORIENTAL Trials: the Re-emergence of J-Curve Ghost? Hamamoto, Yoshiyuki; Koshiyama, Hiroyuki // Japanese Clinical Medicine;2011, Issue 2, p25 

    It still remains unknown whether angiotensin-receptor blockers (ARBs) are cardioprotective in patients with type 2 diabetes. The recent two clinical trials, the ROADMAP and the ORIENT, have suggested that fatal cardiovascular events or cardiovascular deaths were unexpectedly higher in olmesartan...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics