Renal Lesions in Scleroderma

Salomon, Mardoqueo I.; Lamovec, Janez; Tchertkoff, Victor
August 1978
Angiology;Aug1978, Vol. 29 Issue 8, p569
Academic Journal
The article presents information on renal lesion in scleroderma. With respect to a clinical case, the positive immunofluorescent staining in one small artery for complement may represent nonspecific nonimmunologic hyalinization of plasma proteins (plasmatic insudation). However the absence of albumin and fibrinogen is difficult to explain if this is the case. The glomeruli were negative for immunoglobulin and complement but did show slight, finely granular staining for fibrinogen along the glomerular capillary walls. This might represent intravascular coagulation or the sequelae of it in a subendothelial position.


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