TITLE

Hemodynamic Effects of Phentolamine in Valvular Abnormalities

AUTHOR(S)
Gould, Lawrence; Reddy, C. V. R.; Kim, S. G.; Oh, K. C.
PUB. DATE
December 1978
SOURCE
Angiology;Dec1978, Vol. 29 Issue 12, p898
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Seven patients with mitral insufficiency and seven patients with aortie insufficiency were studied by right and left heart catheterization. Hemodynamic observations were made during a control period and during die infusion of phentolaminc. Significant declines in the pulmonary artery mean pressure, left ventricular end diastolic pressure. peripheral resistance, and artenovenous oxygen difference were seen in both groups. The cardiac index increased significantly in the two groups. Phentolamine therapy produced favorable hemo-dynamic effects because of its vasodilating action as well as its positive inotropic effects.
ACCESSION #
16395138

 

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