TITLE

Positive Hemokinetic Effects after Selective Calcium-Antagonism

AUTHOR(S)
Wellens, Donald; Goossens, Toon; Reyntjens, Andre
PUB. DATE
December 1980
SOURCE
Angiology;Dec1980, Vol. 31 Issue 12, p821
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
The article evaluates the therapeutic usefulness of calcium-antagonists in peripheral vascular disorders. For this at least four major functions have to be considered, namely, maintenance or improvement of the myocardial pump function, improvement of arteriolar perfusion, improvement of capillary perfusion and maintenance or improvement of venous return. Calcium-antagonists can improve the tissue perfusion in patients with peripheral circulatory disturbances. Their main advantages are the abolition of vascular spasms and the protection of the erythrocytes against stiffening of their membranes. Some negative hemokinetic effects such as myocardial depression and hindrance of venous return, however, can hamper the positive hemokinetic benefit of this twofold action.
ACCESSION #
16394968

 

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