Phillips, W.L.; Pallin, S.; Crastnopol, P.
November 1969
Angiology;Nov1969, Vol. 20 Issue 10, p628
Academic Journal
The heart may be unable to maintain a satisfactory circulation when part of its muscle has been permanently replaced by fibrous tissue or when the myocardium has been temporarily weakened by congestive heart failure of diverse etiology. Surgical successes that restore the normal mechanics of circulation are manifold. Replacement of stenosed and incompetent cardiac valves with prosthetic counterparts, the correction of congenital cardiac defects, the successful implantation of internal mammary and other arteries in cases of cardiac ischemia resulting from a coronary occlusion are today routine procedures in all cardiac units. The use of pacemakers has prolonged many lives in cases of auriculoventricular block caused by interference with conduction along the bundle of His. Despite the many triumphs of cardiac surgery, the problem of the inadequate or irreversibly damaged myocardium remains largely unsolved. The myocardium may only require temporary assistance in order to allow time for the natural restoration of tissues and function. It is, however, the case of progressive heart failure in which the myocardium is irreparably impaired, that is our most urgent and pressing concern. Replacement with a normal heart or some form of permanent assistance to the damaged heart become the only treatments of choice.


Related Articles

  • University of Maryland Researchers Study Cell Transplantation To Repair Damaged Heart Muscle.  // Ascribe Newswire: Medicine;5/19/2004, p120 

    University of Maryland physicians are taking part in a groundbreaking, multi-center study that could open a new range of treatment options for congestive heart failure. They are investigating whether cells from a patient's leg or arm muscle, when injected into that person's ailing heart, can...

  • INCIDENCE AND CLINICAL SIGNIFICANCE OF LEFT VENTRICULAR ASSIST DEVICE (LVAD) FAILURE. Birks, E. J.; Yacoub, M. N.; Bawles, C. T.; Hipkin, M.; Hardy, J.; Banner, N. R.; Khaghani, A. // Heart;May2004 Supplement 2, Vol. 90, pA28 

    This article focuses on a study related to incidence and clinical significance of left ventricular assist device (LVAD) failure. Management of life threatening LVAD mechanical failure is becoming increasingly important with increasing use of these devices for prolonged periods as a bridge to...

  • Cardiovascular Applications of Stem Cell Therapy. Sadri, Soheil; Mazhari, Ramesh; Sadri, Maziar; Konjedi, Nahal; Shah, Palak // Journal of Stem Cell Research & Therapy;Special2012, Vol. 2 Issue S, Special section p1 

    Despite remarkable progress in medical and surgical therapy for heart disease, congestive heart failure (CHF) and coronary artery disease (CAD) are leading causes of morbidity and mortality in the United States. Although implantation of a left ventricular assist device has recently emerged as a...

  • Paradox of circulating advanced glycation end product concentrations in patients with congestive heart failure and after heart transplantation. Heicfland, A.; Šeboková, K.; Frangiosa, A.; de Santo, L. S.; Cirillo, M.; Rossi, F.; Cotrufo, M.; Perna, A.; Klassen, A.; Schinzel, R.; de Santo, N. G. // Heart;Nov2004, Vol. 90 Issue 11, p1269 

    Objectives: To analyse circulating concentrations of advanced glycation end products (AG Es) in patients with severe congestive heart failure (CHF) and after heart transplantation; to identify the potential contribution of kidney function to plasma AGE concentrations; and to determine whether...

  • Extracorporeal membrane oxygenation to cardiopulmonary bypass with a single circuit exposure. Rogers, Kellie; Owens, Tami; Griffin, Dee Ann; Frey, Talya // Perfusion;Sep2005, Vol. 20 Issue 5, p295 

    Due to the short supply of donor organs available, many patients decompensate or die while waiting for transplantation. Options for mechanical support for infants and pediatrics with congenital heart disease are limited because of the patient's size and device availability. Extracorporeal...

  • Aortico-Right Atrial Tunnel in an Infant. Matter, Mohamed; Elgamal, Mohamed-Adel; Abdel Rahman, Ashraf; Almarsafawy, Hala // Pediatric Cardiology;Aug2011, Vol. 32 Issue 6, p849 

    The article presents a case study of a 2-months old baby girl with symptoms of congestive heart failure. It says that chest radiography showed mild cardiomegaly and multislice computed tomography (CT) angiography was conducted which confirmed the diagnosis of aorta-right atrial tunnel (ARAT). It...

  • Alterations in the Natriuretic Hormone System Related to Cardiopulmonary Bypass in Infants with Congestive Heart Failure. Costello, J.M.; Backer, C.L.; Checchia, P.A.; Mavroudis, C.; Seipelt, R.G.; Goodman, D.M. // Pediatric Cardiology;Jul/Aug2004, Vol. 25 Issue 4, p347 

    This study examined changes in the natriuretic hormone system in five infants with congestive heart failure (CHF) due to intracardiac left-to-right shunting who were exposed to cardiopulmonary bypass (CPB) during surgical repair. Plasma concentrations of three hormones [atrial natriuretic...

  • Patient Selection for Cardiac Resynchronization Therapy. Lopez, J. Alberto // Texas Heart Institute Journal;2005, Vol. 32 Issue 2, p207 

    Discusses the methods for identifying patients with congestive heart failure who may best respond to cardiac resynchronization therapy. Significance of cardiac resynchronization therapy; Findings of a study on the response of patients with ischemic and those with nonischemic cardiomyopathy to...

  • ENERGIZE YOUR HEART, SAVE YOUR LIFE. Goepp, Julius G. // Life Extension;May2008, Vol. 14 Issue 5, p46 

    The article reports on the low-cost carbohydrate molecule, D-ribose, which can prevent cell damage during heart attack and help to rejuvenate heart muscles. D-ribose supplementation has been depicted to boost heart muscle function after a heart attack and to improve blood pumping to people with...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics