All in the Family: Matrimonial Mitral Valve Clicks

Desser, Kenneth B.; Bokhari, S. Ismail; Benchimol, Alberto; Romney, David
May 1981
Angiology;May1981, Vol. 32 Issue 5, p355
Academic Journal
Mitral valve clicks with or without late systolic murmurs were detected in genetically unrelated marital partners of 5 families. The first family represented 2 successive nonconsanguineous marital unions with 3 generations of mitral valve clicks. The second family included 1 natural and 2 adopted children with clinical and echographic evidence of mitral valve prolapse. The third family was comprised of asymptomatic parents, both with nonejection clicks and mitral valve prolapse, whose daughter presented 3 years previously with syncope, palpitations, and combined mitral and tricuspid valve prolapse. The fourth family had 3 members with auscultatory and ultrasonic manifestations of billowing mitral valve, whereas the fourth member had "silent mitral valve prolapse." The fifth family represented a mother with auscultatory and echographic evidence of mitral valve prolapse; her 14-year-old daughter had both mitral and tricuspid valve prolapse, whereas the son had a bicuspid aortic valve. Both children were products of a prior marriage, and her husband has symptomatic mitral valve prolapse. We conclude that matrimonial mitral valve prolapse probably reflects the purported (6-10%) prevalence of this disorder in the general population. The consequences of such marital union on progeny is currently unclear and warrants future investigation.


Related Articles

  • Bicuspid aortic valves: increased morbidity but not mortality.  // Heart;Jan2009, Vol. 95 Issue 2, p171 

    The article discusses a study on the disease progression and cardiac outcomes of patients with bicuspid aortic valves. In a cohort study of 642 adults, 28 deaths occurred during the nine-year follow-up period, while 161 primary cardiac events occurred in 161 patients. Predictors of cardiac...

  • Cardiothoracic ratio and left heart valves regurgitation. Olgar, Şeref // Anatolian Journal of Cardiology / Anadolu Kardiyoloji Dergisi;Jun2007, Vol. 7 Issue 2, p150 

    The article comments on the relation between cardiothoracic ratio and left heart valves regurgitation. The traditional linear cardiothoracic ratio has been found to show an inverse correlation with the left ventricular ejection fraction. Cardiothoracic ratio and cardiac frontal area do not...

  • Transcatheter aortic valve implantation in a patient with previous Starr-Edwards mitral valve prosthesis. Rahman, Mohammed Shamim; Roy, David; Brecker, Stephen J. // Heart;Feb2013, Vol. 99 Issue 3, p217 

    The article presents a case study of a 75-year-old woman with a Starr-Edwards valve in the mitral position inserted for mitral stenosis who was taken to the emergency room due to symptomatic severe aortic stenosis. She underwent a transfemoral procedure for transcatheter aortic valve...

  • Bicuspid aortic valve disease. Losenno, Katie L.; Chu, Michael W. A. // CMAJ: Canadian Medical Association Journal;12/10/2013, Vol. 185 Issue 18, p1599 

    The article focuses on bicuspid aortic valve disease, the most common congenital heart disease in developed countries. Topics discussed include the disease's higher occurrence in men, its possible association with other heart and aorta abnormalities, and valvular and aortic complications among...

  • New quantitative three-dimensional echocardiographic indices of mitral valve stenosis. Gabriel Valocik; Otto Kamp; Herman Mannaerts; Cees Visser // International Journal of Cardiovascular Imaging;Dec2007, Vol. 23 Issue 6, p707 

    Abstract Background  We studied the value of quantitative three-dimensional echocardiography (3DE) in the evaluation of mitral valve stenosis using the measurement of the mitral valve area (MVA) with two new indices: the doming volume and mitral valve volume. Methods and...

  • Mitral mechanical heart valves: in vitro studies of their closure, vortex and microbubble formation with possible medical implications. Milo, Simcha; Rambod, Edmond; Gutfinger, Chaim; Gharib, Morteza // European Journal of Cardio-Thoracic Surgery;Sep2003, Vol. 24 Issue 3, p364 

    Objective: The goal of the present work was to create the closest possible in vitro fluid dynamic environment in which prosthetic mitral valves in the patients’ hearts function, in order to demonstrate whether microbubbles are generated, and if yes, under what conditions and at which...

  • Changing demographics of valvular heart disease and impact on surgical and transcatheter valve therapies. Vahanian, Alec; Iung, Bernard; Himbert, Dominique; Nataf, Patrick // International Journal of Cardiovascular Imaging;Dec2011, Vol. 27 Issue 8, p1115 

    Valvular heart disease remains frequent in industrialised countries since the decrease in frequency of rheumatic heart diseases has been accompanied by an increase in degenerative valve diseases. The prevalence of valvular disease increases sharply with age, as a consequence of the predominance...

  • Heart Valve Surgery Today-Indications, Operative Technique, and Selected Aspects of Postoperative Care in Acquired Valvular Heart Disease. Geißler, Hans Joachim; Schlensak, Christian; Südkamp, Michael; Beyersdorf, Friedhelm // Deutsches Aerzteblatt International;3/27/2009, Vol. 106 Issue 13, p4 

    The article presents information on various heart valve diseases, including their indications, operative technique, and aspects of postoperative care in acquired valvular heart disease. Some of the heart valve diseases are aortic stenosis, aortic regurgitation, mitral stenosis, tricuspid...

  • Remote ischaemic preconditioning reduces myocardial injury in patients undergoing heart valve surgery: randomised controlled trial. Jian-Jiang Xie; Xiao-Long Liao; Wen-Guang Chen; Da-De Huang; Feng-Jun Chang; Wen Chen; Zhao-Liu Luo; Zhi-Ping Wang; Jing-Song Ou // Heart;Mar2012, Vol. 98 Issue 5, p384 

    Objective To determine whether remote ischaemic preconditioning (RIPC) is cardioprotective in patients undergoing heart valve replacement. Design Single-blinded, randomised controlled trial Setting Tertiary referral hospital in China Patients Adult patients (31e72 years) undergoing mitral valve,...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics