TITLE

Lymphatic Abnormalities in Protein-Losing Gastropathy, Especially in Ménétrier's Disease

AUTHOR(S)
Miura, Soichiro; Asakura, Hitoshi; Tsuchiya, Masaharu
PUB. DATE
May 1981
SOURCE
Angiology;May1981, Vol. 32 Issue 5, p345
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Histopathologic and lymphographic studies were performed in 4 patients with protein-losing gastropathy to elucidate the degree of lymphatic disorders and their contribution to clinical features. Histologic examination of gastric mucosa showed various degrees of hyperplasia of the surface epithelium and cystic dilatation of glands, which were considered to be characteristic findings of protein losing gastropathy. Moreover, in 3 of 4 patients there were edematous change of the lamina propria or the submucosa, and marked lymphangiectasia was seen in the submucosa of 3 patients and in the lamina propria of the other. Performed lymphograms showed an increase in the number of lymphatic vessels and lymph nodes in the iliopelvic and lumbar regions of 2 of the patients. This high incidence of lymphatic abnormalities in patients with protein-losing gastropathy suggested that such systemic lymphatic disorders were an important etiologic factor. However, such abnormalities in lymphatic system were not demonstrated in all cases of protein-losing gastropathy. Therefore, lymphatic disorders were not considered to be the primary cause of gastric protein loss, but the important factor that modifies the variety of lost protein and its clinical features.
ACCESSION #
16394556

 

Related Articles

  • Lack of difference of gastric mucosal histology between functional dyspepsia subgroups according to Rome III criteria. Uslan, Ihsan; Acarturk, Gursel; Husniye, Fatma; Songur, Yildiran // HealthMed;2013, Vol. 7 Issue 6, p1788 

    Background: The aim of this study was to investigate the histopathological changes in gastric mucosa of patients with functional dyspepsia according to the Rome III criteria. Methods: Fifty consecutive patients diagnosed as functional dyspepsia by Rome III criteria were included into the study....

  • Transcriptome Reveals 1400-Fold Upregulation of APOA4-APOC3 and 1100-Fold Downregulation of GIF in the Patients with Polycythemia-Induced Gastric Injury. Li, Kang; Gesang, Luobu; Dan, Zeng; Gusang, Lamu; Dawa, Ciren; Nie, Yuqiang // PLoS ONE;10/20/2015, Vol. 10 Issue 10, p1 

    High-altitude polycythemia (HAPC) inducing gastric mucosal lesion (GML) is still out of control and molecular mechanisms remain widely unknown. To address the issues, endoscopy and histopathological analyses were performed. Meanwhile, microarray-based transcriptome profiling was conducted in the...

  • Vulval lymphangiectasia secondary to tubercular lymphadenitis. Singh, Nidhi; Kumari, Rashmi; Thappa, Devinder Mohan // Indian Journal of Sexually Transmitted Diseases;2007, Vol. 28 Issue 1, p38 

    A 25-year-old married woman presented with swelling of vulva with oozing of watery fluid from vulval skin surface for the past 8 years. She also complained of swelling in the inguinal region (occasionally painful) on both sides for the past 8 years. Local genital examination revealed diffuse...

  • Chemoprevention of Precancerous Gastric Lesions With Antioxidant Vitamin Supplementation: A Randomized Trial in a High-Risk Population. Plummer, Martyn; Vivas, Jorge; Lopez, Gladys; Bravo, Juan Carlos; Peraza, Simon; Carillo, Elsa; Cano, Elsa; Castro, Denis; Andrade, Olga; Sanchez, Victor; Garcia, Rita; Buiatti, Eva; Aebischer, Claude; Franceschi, Silvia; Oliver, Walter; Muñoz, Nubia // JNCI: Journal of the National Cancer Institute;1/17/2007, Vol. 99 Issue 2, p137 

    Background Gastric cancer is one of the most common malignancies worldwide. Histopathologic studies have identified a sequence of changes in the gastric mucosa that mark the slow progression from normal tissue to carcinoma. Epidemiologic evidence suggests that a diet rich in fresh fruit and...

  • Clinical approach to lymphadenopathy. Abba, Abdullah A.; Khalil, Mohamed Z. // Annals of Nigerian Medicine;Jan2012, Vol. 6 Issue 1, p11 

    Lymphadenopathy (LAP) is a common clinical finding that may be localized, limited or generalized. The enlargement of a lymph node, due to primary disease or secondary cause, is of concern to both patients and clinicians, particularly, if the underlying pathology is a malignant disease. Lymph...

  • Portal Hypertensive Duodenopathy: Clinical, Endoscopic, and Histopathologic Profiles. Barakat, Maha; Mostafa, Mohamed; Mahran, Zeinab; Soliman, Abdel-Ghani // American Journal of Gastroenterology;Dec2007, Vol. 102 Issue 12, p2793 

    OBJECTIVE: Description of the clinical, endoscopic, and histopathologic detailed profiles of duodenal affection in portal hypertensive patients. METHODS: A total of 105 patients with chronic liver disease and portal hypertension (PH) were included, upper endoscopy was performed, and two duodenal...

  • Gastric mucosal changes induced by polyethylene glycol 400 administered by gavage in rats. Ueda, Yoshihide; Tsuboi, Masaru; Ota, Yasufumi; Makita, Maki; Aoshima, Takuya; Nakajima, Madoka; Narama, Isao // Journal of Toxicological Sciences;Dec2011, Vol. 36 Issue 6, p811 

    Polyethylene glycol 400 (PEG 400) is widely used with a variety of pharmaceutical formulations, and is often added to dosing formulations in preclinical toxicity studies. The aim of the present study was to characterize the effects of PEG 400 on the rat gastrointestinal tract. Three dosage...

  • Protective effect of fenugreek seeds ( Trigonella foenum graecum) extract against experimental gastric ulcer in rats. Azari, Omid; Kheirandish, Reza; Shojaeepour, Saeedeh // Comparative Clinical Pathology;Nov2014, Vol. 23 Issue 6, p1743 

    Trigonella foenum graecum, (Fenugreek) is used in traditional medicine for its anti-inflammatory, antiseptic, and antidiabetic properties. The present study was designed to investigate the protective effects of fenugreek seed extract on experimentally induced gastric mucosal ulcer in rats. In...

  • Histopathological changes of gastric mucosa following oral administration of fumonisin B1 in mice. Tavasoly, Abbas; Kamyabi-moghaddam, Zahra; Alizade, Alimohammad; Mohaghghi, Mohhmmadali; Amininajafi, Fatemeh; Khosravi, Alireza; Rezaeian, Maryam; Solati, Amirali // Comparative Clinical Pathology;May2013, Vol. 22 Issue 3, p457 

    Fumonisin B1 is a common secondary metabolite produced by Fusarium moniliforme that occurs in corn and corn-based foods. This mycotoxin is toxic to many species of laboratory and domestic animals and is known to induce a variety of diseases such as hepatic cancer and renal and hepatic...

Share

Read the Article

Courtesy of VIRGINIA BEACH PUBLIC LIBRARY AND SYSTEM

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics