TITLE

Circadian Rhythm of Hourly Ventricular Arrhythmia Frequency in Man

AUTHOR(S)
Canada, W. Britt; Woodward, Wayne; Lee, Gerritl; DeMaria, Anthony; Low, Reginald; Mason, Dean T.; Laddu, Atul; Shapiro, William
PUB. DATE
April 1983
SOURCE
Angiology;Apr1983, Vol. 34 Issue 4, p274
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Three twenty-four hour electrocardiographic recordings from 164 untreated patients were analyzed. A clear, statistically significant, diurnal pattern in hourly ventricular arrhythmia frequency was found. It was consistent across days and between seven diagnostic groups. A high frequency Noon to 4:00 PM peak contrasted with a low frequency 1:00 AM to 5:00 AM trough with zero hourly frequencies not uncommonly present. These findings appear applicable to large ambulatory populations and may well influence the design of future investigations of modalities which alter ventricular arrhythmia frequency.
ACCESSION #
16391365

 

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