TITLE

Serial Hemodynamic Studies During the Treatment of Congestive Heart Failure With Isolated Low-Dose Oral Prazosin Therapy

AUTHOR(S)
Reyns, Philippe; Romney, David; Desser, Kenneth B.; Benchimol, Alberto
PUB. DATE
December 1979
SOURCE
Angiology;Dec1979, Vol. 30 Issue 12, p850
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Prazosin was administered orally at a maximal dose of 2 mg every 6 hours to 4 patients with congestive heart failure (CHF) who had not received either digitalis or diuretics for 72 hours before therapy. Three of the 4 patients had hypertensive and arteriosclerotic heart disease. Hemodynamic monitoring indicated a significant reduction of preload and afterload with a concomitant rise in the cardiac index. We concluded that isolated low-dose oral prazosin has salutary effects on indices of hemodynamic function in selected patients.
ACCESSION #
16390786

 

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