TITLE

THE EFFECT ON THE CORONARY ARTERIES OF A NEW SUSTAINED ACTION VASODILATOR

AUTHOR(S)
Hirshleifer, Irving
PUB. DATE
February 1958
SOURCE
Angiology;Feb1958, Vol. 9 Issue 1, p31
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
1. Twenty-three patients with coronary artery disease associated with angina pectoris were treated with 80 mg Peritrate sustained action tablets—one tablet twice a day; 17 showed a favorable response. 2. Three patients who did not respond clinically to nitroglycerine did not respond to Peritrate sustained action tablets. 3. One patient who had headache with nitroglycerine was similarly affected by Peritrate sustained action tablets for a period of 12 hours. 4. No untoward effects resulted from Peritrate sustained action tablets except for epigastric distress in one patient which was not a cause for discontinuing the drug. 5. Eighty mg Peritrate sustained action tablet is a long acting vasodilator with a clinical effectiveness of approximately 12 hours and is the drug of choice in the long term treatment of angina pectoris. 6. Peritrate sustained action tablets give a definite regimen to a patient with angina pectoris thus helping to break the undesirable cycle of anxiety → angina → nitroglycerine → further anxiety, that these patients usually experience. 7. Peritrate sustained action tablets reduce the frequency of anginal attacks and thus reduce nitroglycerine requirements, give patient reassurance, increase effort tolerance and thus permit the patient to live a more normal life.
ACCESSION #
16389184

 

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