Johnson, Shirley A.; Priest, Edward M.; Caldwell, M. June
December 1959
Angiology;Dec1959, Vol. 10 Issue 6, p435
Academic Journal
The interrelationships of prothrombin, Factor VII and PTC as affected by administration of the oral anticoagulants were investigated. When these three blood coagulation components were greatly reduced, fat soluble vitamin K1 and water soluble vitamin K1 were given to the patients. In spite of the very minimal differences in molecular configuration between these two compounds, different blood coagulation components appeared in the plasma and serum of the patient. Both vitamin K1 compounds reduced the prothrombin time.


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