elye, Hans; Bajusz, E�rs
December 1959
Angiology;Dec1959, Vol. 10 Issue 6, p412
Academic Journal
Experiments on rats were performed to examine the effect of sodium deficiency upon various experimental cardiac lesions, which differ widely from each other in both their causative agents and their histologic characteristics. It was found that sodium deficiency significantly protected the heart against the production of necrosis, inflammation and/or calcification by dihydrotachysterol (DHT), plasmocid and papain. In fluorocortisol conditioned, sodium deficient animals the cardiac necrosis eliciting effect of neuromuscular effort was also markedly inhibited. A reduction of the severity and incidence of the �spotty myolysis� normally due to the administration of noradrenaline and vasopressin was suggestive, but not statistically significant. On the other hand, combined administration of DHT + calcium acetate produced fatal, acute suppurative myocarditis of an equal degree in the (control and sodium deficient rats. Thus, the protective effect of sodium deficiency against the calcifying and necrotizing actions of DHT was completely abolished by the concurrent administration of calcium acetate. The importance of sodium in the pathogenosis of cardiac necroses and the possible role of electrolyte-steroid interactions in calcifying and necrotizing cardiac diseases are briefly discussed on the basis of those and previous observations.


Related Articles

  • Therapy for Late Post Infarction Ventricular Tachycardia. Somberg, John C.; Butler, Brenda; Torres, Vilma; Tepper, David; Keren, Gad; Siegel, Louis; Jentzer, John; Miura, Dennis S. // Angiology;Mar1985, Vol. 36 Issue 3, p181 

    Non-sustained ventricular tachycardia (VT) in the late post myocardial infarction (MI) period (7-21 days) has been reported to be a predictor of sudden death. We suspected that patients with 3 beat VT on Holter monitoring in the late infarction period would demonstrate electrical instability at...

  • Circadian Variation In Onset Of Myocardial Infarction In Diabetics (NIDDM) And Non-Diabetics. Sahoo, Bismaya; Mishra, Priyadarshini // Australasian Medical Journal;Aug2010, Vol. 3 Issue 8, p520 

    Introduction A number of retrospective and prospective studies have demonstrated a peak in the onset of Myocardial Infarction in the morning hours and a trough at night. Diabetes is associated with an abnormal circadian pattern of several physiologic processes. This study was undertaken to...

  • Atlas-Based Quantification of Cardiac Remodeling Due to Myocardial Infarction. Zhang, Xingyu; Cowan, Brett R.; Bluemke, David A.; Finn, J. Paul; Fonseca, Carissa G.; Kadish, Alan H.; Lee, Daniel C.; Lima, Joao A. C.; Suinesiaputra, Avan; Young, Alistair A.; Medrano-Gracia, Pau // PLoS ONE;Oct2014, Vol. 9 Issue 10, p1 

    Myocardial infarction leads to changes in the geometry (remodeling) of the left ventricle (LV) of the heart. The degree and type of remodeling provides important diagnostic information for the therapeutic management of ischemic heart disease. In this paper, we present a novel analysis framework...

  • A practical assessment of the short-term in vitro stability of troponin I at the 99th percentile. Peake, Roy W. A.; Deans, Kevin A.; Croal, Bernard L. // Annals of Clinical Biochemistry;Jul2011, Vol. 48 Issue 4, p377 

    Background: Serial troponin measurement is important for the diagnosis of myocardial infarction. As troponin concentrations approach the cut-off for detectable myocardial necrosis, smaller changes in troponin as a result of decreased in vitro stability may be sufficient to generate changes of...

  • Lightning-Induced Myocardial Injury A Case Report with Management. Sinha, Amarendra Kumar // Angiology;May1985, Vol. 36 Issue 5, p327 

    A young patient of lightning induced myocardial injury with chest pain is described. Electro-cardiogram mimicked true myocardial infarction (due to coronary artery disease). Practical aspects of case management is discussed. Use of short course of steroid helped in early recovery.

  • CORRELATION OF SYSTOLIC AND DIASTOLIC INTERVALS IN VARIOUS CARDIAC CONDITIONS. Bhat, Pachalla K.; Luisada, Aldo A. // Angiology;Nov1977, Vol. 28 Issue 11, p729 

    We studied this interval further in several pathologic conditions and showed that it may be typically abbreviated in one of them (systemic hypertension) and typically prolonged in conditions associated with myo-cardial fibrosis or scarring (coronary heart disease and myocardial infarct) with an...

  • Arachidonic Acid Metabolites in Acute Myocardial Infarction. Takase, Bonpei; Maruyama, Toshiharu; Kurita, Akira; Uehata, Akimi; Nishioka, Toshihiko; Mizuno, Kyoichi; Nakamura, Haruo; Katsura, Kenichiro; Kanda, Yoshikazu // Angiology;Jul1996, Vol. 47 Issue 7, p649 

    Abnormalities of arachidonic acid metabolism are implicated in spasm and thrombosis in coronary arteries. Therefore, arachidonic acid metabolites were examined in patients with acute myocardial infarction (AMI). Plasma levels of thromboxane B2 (TXB2), 6-ketoprostaglandin F1a, (6KPGF1a),...

  • Blood Pressure Level and Incidence of Myocardial Infarction Among Patients Treated for Hypertension. Kaplan, Robert C.; Psaty, Bruce M.; Heckbert, Susan R.; Smith, Nicholas L.; Lemaitre, Rozenn N. // American Journal of Public Health;Sep99, Vol. 89 Issue 9, p1414 

    Objectives. This study examined the relationship between achieved blood pressure and risk of myocardial infarction among patients treated for hypertension. Methods. Blood pressure and other cardiovascular risk factors were assessed among 718 myocardial infarction case patients and 2136 matched...

  • Engaging patients in managing their cardiovascular health. Newman, S. // Heart;Jun2004 Supplement 4, Vol. 90, piv9 

    Psychological factors play a major part in the impact, course, and treatment of cardiovascular disease. Patients cognitions and emotions feed into their responses to their illness and its treatments and can, for example, affect the likelihood of attendance at cardiac rehabilitation programmes....


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics