TITLE

Myoglobinemia is an Early and Quantitative Index of Acute Myocardial Infarction

AUTHOR(S)
Willerson, James T.
PUB. DATE
May 1978
SOURCE
Angiology;May1978, Vol. 29 Issue 5, p386
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Systemic arterial compliance was measured in 22 patients with permanent essential hypertension and compared with 11 sex- and age-matched normal subjects. Determinations were made from analysis of the monoexponential blood pressure-time curve during diastole, according to a simple visco-elastic model. Arterial compliance was significantly decreased (P « 0.001) in hypertensives. In the overall population, arterial compliance was negatively correlated to age (P « 0.005) and blood pressure (P « 0.001), suggesting that the changes in compliance could be attributable to the level of blood pressure per se and/or to the rigidity of the arterial wall. Administration of vasoactive substances (angiotensin and sodium nitroprusside) enabled a strong negative relationship (P « 0.01) between arterial compliance and diastolic blood pressure to be demonstrated in each individual. The slope of the curve was not dependent on age and represented the ability to decrease compliance per unit rise in pressure. The slope was steeper in hypertensives, suggesting a change reactivity of the arterial wall in these patients.
ACCESSION #
16388168

 

Related Articles

  • Hypertension meeting highlights new theories. Pfeiffer, Naomi // Drug Topics;7/24/2006, Vol. 150 Issue 14, p18 

    The article examines the effectiveness of aliskerin drug for treating mild to moderate hypertension. Aliskerin is the first in a new class of direct renin inhibitors to provide blood pressure control with or without a diuretic. The drug counteracts the tendency of hypertensives to have early...

  • HEMODYNAMIC CHANGES IN ARTERIOSCLEROTIC VS. NON-ARTERIOSCLEROTIC RATS DURING THE ACUTE STAGES OF MYOCARDIAL INFARCTION. Colfer, H. T.; Iams, S. G.; Wexler, B. C. // Angiology;Jan1976, Vol. 27 Issue 1, p32 

    Non-arteriosclerotic (virgin), male and female, Sprague-Dawley rats and arteriosclerotic (breeder), male and female rats were subjected to an acute myocardial infarct when injected with two subcutaneous doses of isoproterenol. Female rats, especially female breeder rats with advanced...

  • THE ASCOT AFTERMATH WHAT GPS NEED TO KNOW.  // Pulse;10/8/2005, Vol. 65 Issue 39, p44 

    Reports that Anglo-Scandinavian Cardiac Outcomes Trial (ASCOT) results published has plunged hypertension management into turmoil. Announcement on the revision of Anglo-Scandinavian Cardiac Outcomes Trial's guidance; Reduction on the primary endpoint of non-fatal myocardial infarction and fatal...

  • CORRELATION OF SYSTOLIC AND DIASTOLIC INTERVALS IN VARIOUS CARDIAC CONDITIONS. Bhat, Pachalla K.; Luisada, Aldo A. // Angiology;Nov1977, Vol. 28 Issue 11, p729 

    We studied this interval further in several pathologic conditions and showed that it may be typically abbreviated in one of them (systemic hypertension) and typically prolonged in conditions associated with myo-cardial fibrosis or scarring (coronary heart disease and myocardial infarct) with an...

  • Left ventricul pseudoaneurysm after posteroinferolateral wall myocardial infarction. Zvizdić, Faris; Haračić, Azra; Kulić, Mehmed; Durak, Azra; Džubur, Alen; Mišeljić, Sanja // Medical Journal;Jul-Sep2015, Vol. 21 Issue 3, p231 

    Left ventricular pseudoaneurysm is a rare but potentially lethal complication of acute myocardial infarction. Although relatively little is known regarding their true incidence and possible presentations, pseudoaneurysms have a greater tendency to rupture in comparison with a true aneurysm ....

  • New evidence in hypertension and hyperlipidaemia. Chapman, N. // Heart;Jun2004 Supplement 4, Vol. 90, piv14 

    The benefits of blood pressure lowering on the risk of cardiovascular disease are seen with all commonly used classes of antihypertensive drugs. Although different drug classes may have different effects on cause specific outcomes (such as myocardial infarction or stroke), no differences are...

  • Multivessel Spontaneous Coronary Artery Dissection in a Patient with Severe Systolic Hypertension: A Possible Association. Greenblatt, Jeff M.; Kochar, Gupreet S.; Albornoz, M. Anthony // Angiology;Jun1999, Vol. 50 Issue 6, p509 

    Spontaneous coronary artery dissection (SCAD) is an uncommon cause of myocardial ischemia and infarction. Hypertension has not been associated with SCAD. The authors report multivessel SCAD in an elderly woman with severe systolic hypertension. They postulate that hypertension of this degree may...

  • The renal consequences of arterial hypertension. Mountokalakis, Theodore D. // Kidney International;May1997, Vol. 51 Issue 5, p1639 

    This article presents information on a case related to renal consequences of arterial hypertension. A 57-year old man was referred to the Hypertension Clinic of the University Department of Medicine at the Sotiria General Hospital of uncontrolled hypertension and renal insufficiency. He was a...

  • Is treatment of hypertension with acetylcholine esterase inhibitors (ACEIs) superior to other antihypertensives in preventing significant cardiovascular events and death in patients with type 2 diabetes? McConaghy, John R. // Journal of Family Practice;Nov2000, Vol. 49 Issue 11, p980 

    The article presents a study which examined whether the treatment of hypertension with acetylcholine esterase inhibitors (ACEI) is superior to other antihypertensives in the prevention of significant cardiovascular events and death in diabetics. The study recommended that lowering blood pressure...

Share

Read the Article

Courtesy of VIRGINIA BEACH PUBLIC LIBRARY AND SYSTEM

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics