TITLE

ISOVOLUMIC RELAXATION TIME IN NORMAL SUBJECTS AND PATIENTS WITH CARDIAC DISEASE: COMPARISON OF DETERMINATIONS MADE WITH ECHOCARDIOGRAPHIC TECHNIQUES AND APEX CARDIOGRAPHY

AUTHOR(S)
Araoye, Matthew A.; Rubler, Shirley; Holford, Fred D.
PUB. DATE
January 1978
SOURCE
Angiology;Jan1978, Vol. 29 Issue 1, p7
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Isovolumic relaxation time (IVRT) was determined in 17 controls and 41 patients. Nine patients had ischemic heart disease (IHD), 7 mitral prolapse (MVPS). 13 hypertension (HBP), 7 pregnancy (P), and 5 cardiomyopathy (CM). Echocardiographic measurements of IVRT were made from the aortic second sound to the rapid opening of the mitral valve (A2D�). Determinations by apexcardiography were made from the aortic second sound to the 0 point (A2O). The IVRT was distinctly shorter when assessed by A2D' than by conventional apexcardiography in controls (69.2 � 16.4 msec vs 118.7 � 16.5 msec), and in patients with cardiac disease. The IVRT in 9 older normal controls (mean age 47.7 years) was longer than in 8 younger ones (age 26.3 � 4.9 years). Patients with myocardial disease (IHD. HBP, and CM) had prolonged IVRTs when compared to normal subjects. Pregnant subjects had shortened intervals. IVRT may be a sensitive indicator of disturbances in myocardial contractility and may be shortened and enhanced contractility.
ACCESSION #
16388030

 

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