The Therapy of Peripheral Vascular Ulcers -- Surgical Management

Lirn, Leonardo T.; Michuda, Maryanne; Bergan, John J.
September 1978
Angiology;Sep1978, Vol. 29 Issue 9, p654
Academic Journal
The article focuses on the therapy of peripheral vascular ulcers. Unlike arterial ischemic ulcers caused by arteriosclerotic occlusive disease, venous ulcers, though comprising 90% of ulcers in the leg, are less understood, often disregarded and considered a poor second cousin to the arterial side. Forty to fifty per cent of venous ulcers are principally caused by post-thrombotic deep venous and perforator vein incompetence. The remainder are due to primary incompetence of the perforating veins and long-standing primary varicose veins with incompetent perforators. It has been shown by recent non-invasive studies that over half of the patients with deep venous thrombosis are asymptomatic and of those with leg symptoms only 50% will be positive.


Related Articles

  • Factor V Leiden Mutation in a Case with Ischemic Stroke: Which Relationship? Orlandi, Giovanni; Pellegrinetti, Alberto; Fioretti, Cristina; Martini, Antonio; Murri, Luigi // Angiology;Jan1998, Vol. 49 Issue 1, p79 

    A 50-year-old man presented spontaneous internal carotid artery dissection with ischemic stroke. He had a history of deep venous thrombosis, and an activated protein C resistance due to factor V Leiden mutation was documented. He showed no other vascular risk factor. This unusual case puts the...

  • Pathophysiology of Venous Leg Ulceration--An Update. Dormandy, John A. // Angiology;Jan1997, Vol. 48 Issue 1, p71 

    The microcirculatory component of the pathophysiology of venous ulceration is now attracting considerable research interests, but is still far from fully elucidated. Currently, the central role is filled by the inappropriately activated white cell and its interaction with the endothelium....

  • Efficacy of Daflon 500 mg in Venous Leg Ulcer Healing: A Double-Blind, Randomized, Controlled Versus Placebo Trial in 107 Patients. Guilhou, Jean-Jacques; Dereure, Olivier; Marzin, Loïc; Ouvry, Pierre; Zuccarelli, François; Debure, Clélia; van Landuyt, Hervé; Gillet-Terver, Marie-Noélle; Guillot, Bernard; Levesque, Hervé; Mignot, Jean; Pillion, Gérard; Février, Benoit; Dubeaux, Dominique // Angiology;Jan1997, Vol. 48 Issue 1, p77 

    The objective of this study was to evaluate the efficacy of Daflon® 500 mg (Dios)* in venous ulcers. A multicenter, double-blind, randomized, controlled versus placebo (Plac) trial was conducted, with stratification according to the size of ulcer (⩽ 10 cm and > 10 cm). The protocol...

  • THROMBOSIS AND RECANALIZATION OF VEINS USED AS VENOUS GRAFTS. Dale, W. Andrew // Angiology;Dec1961, Vol. 12 Issue 12, p603 

    Focuses on the high incidence of recanalization of veins which thrombosed early in the postoperative where delayed phlebography or casual examination of autopsy material would fail to indicate the earlier thrombosis which later resulted in a lumen by the process of recanalization. Incidence of...

  • The Influence of Limb Elevation, Examination Technique, and Outflow System Design on Venous Plethysmography. Tripolitis, A. J.; Blackshear Jr., W. M.; Bodily, K. C.; Thiele, B. L.; Strandness Jr., D. E. // Angiology;Mar1980, Vol. 31 Issue 3, p154 

    The effect of limb elevation and the design of the thigh cuff outflow system on venous capacitance and venous outflow, as determined by strain gauge plethysmography, was reviewed in a group of normal limbs without evidence of deep venous thrombosis. We improved the reliability of plethysmography...

  • Very Late Stent Fracture Associated With a Sirolimus-eluting Stent Leong, D.P.; Dundon, B.K.; Puri, R.; Yeend, R.A.S. // Heart, Lung & Circulation;Oct2008, Vol. 17 Issue 5, p426 

    Late stent thrombosis (>1 year after implantation) is a recognised complication involving drug-eluting stents. Stent fracture is increasingly being reported as a complication of drug-eluting stent, and in particular sirolimus-eluting stent use. We report the case of very late sirolimus-eluting...

  • Delineating the Hemostaseome as an aid to individualize the analysis of the hereditary basis of thrombotic and bleeding disorders. Fechtel, Kim; Osterbur, Marika L.; Kehrer-Sawatzki, Hildegard; Stenson, Peter D.; Cooper, David N. // Human Genetics;Jul2011, Vol. 130 Issue 1, p149 

    Next-generation sequencing and genome-wide association studies represent powerful tools to identify genetic variants that confer disease risk within populations. On their own, however, they cannot provide insight into how these variants contribute to individual risk for diseases that exhibit...

  • Socioeconomic Impact of Chronic Venous Insufficiency and Leg Ulcers. Ruckley, C. V. // Angiology;Jan1997, Vol. 48 Issue 1, p67 

    Chronic venous insufficiency affects approximately 5% and chronic leg ulcer approximately 1% of the adult population of developed countries. Not only do recent quality of life studies highlight major disability and social impairment but, since this is a condition characterized by chronicity and...

  • Deep Vein Thrombosis Detection by 99m TC-MDP Scanning. Moallem, Anita; Lichsztral, Regina // Angiology;Aug1984, Vol. 35 Issue 8, p515 

    A new observation is reported wherein 99m Tc-MDP is incorporated into recanalizing thrombophlebitis. In one patient with subacute disease, inflammatory vascularity is appreciated during the first one to two minutes after injection. Both patients showed evidence of late phosphate uptake in their...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics