TITLE

Buffer capacity, pH, and flow rate in saliva of children aged 2-60 months with Down syndrome

AUTHOR(S)
Siqueira, Walter Luiz; Bermejo, Patrícia Rota; Mustacchi, Zan; Nicolau, José
PUB. DATE
March 2005
SOURCE
Clinical Oral Investigations;Mar2005, Vol. 9 Issue 1, p26
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
This study measured the flow rate, pH, and buffer capacity of saliva from children with Down syndrome aged 2-60 months. We compared 25 children with Down syndrome with 21 children without Down syndrome. The whole saliva was collected under slight suction and the pH and the buffer capacity were determined using a digital pHmeter. The buffer capacity was measured by titration with 0.01 N HCl. The Down syndrome group demonstrated higher buffer capacity than the control group in the pH ranges of 6.9-6.0, 5.9-5.0, and 4.9-4.0. The flow rate was low in the Down syndrome group. Boys from the Down syndrome group demonstrated higher buffer capacity in the pH ranges 6.9-6.0, 5.9-5.0, and 4.9-4.0 than controls, while girls from the Down syndrome group showed no difference compared with controls. Girls with Down syndrome demonstrated significant difference only in the range of pHi-pH 7.0. Conclusion. These data suggest that the Down syndrome persons present a better buffer capacity, supporting the results observed in several studies which found the low dental caries in persons with Down syndrome.
ACCESSION #
16381390

 

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