TITLE

DIRECT VISUALIZATION OF THE INFLUENCE OF DRUGS ON CAPILLARY UPTAKE OF DYE

AUTHOR(S)
Cocchiara, John L.; Threefoot, Sam A.
PUB. DATE
August 1966
SOURCE
Angiology;Aug1966, Vol. 17 Issue 8, p583
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Direct observation and photography have shown that there are effects by various preparations of drugs on the uptake of substance by capillaries. Meralluride, digoxin, Lyo-hydrodiuril, hyaluronidase and mercaptomerin increased capillary and venous uptake of dyes, whereas PLV-2, epinephrine, norepinephrine, histamine and mercuric chloride decreased of prevented uptake. These data provide further support for an extrarenal action of mercurial diuretics and for the extracardiac actions of digitalis glycosides. Although these data demonstrate the influence of the drugs on capillary absorption, they do not provide an explanation of the mechanisms of action.
ACCESSION #
16378183

 

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