Haan, D.; Tilsner, V.
January 1965
Angiology;Jan1965, Vol. 16 Issue 1, p49
Academic Journal
1. During a two-year-period 125 patients have been followed with regard to their subjective cardiac complaints. 65 of them have been treated with anticoagulants and 60 without. 2. 33.9% of the anticoagulant group continued to have symptoms of angina, 66.1% remained asymptomatic. In the non-anticoagulant group the incidence of pain was 55% while 45% remained free of symptoms. 3. Thirteen cases are reported who have complained of stenocardia or increase of chest pain whenever the prothrombin level was elevated (thromboplastin time of Quick). 4. Basing on the anticoagulant effect of the drug, the results of the study can be interpreted to some extent. The direct effect on the coronary circulation or metabolism of the heart muscle, as presumed by some authors, could neither be affirmed nor denied equivocally by our results.


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