TITLE

INTRA-ARTERIAL THERAPY

AUTHOR(S)
Widmer, L.K.
PUB. DATE
October 1966
SOURCE
Angiology;Oct1966, Vol. 17 Issue 10, p738
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
The author investigates by external monitoring the radioactivity of the foot after injection of Na24, under which conditions the intra-arterial applications leads to an increased concentration in the target tissue territory. With infusion into the superficial femoral artery the concentration is 2.7 times higher than with intravenous infusion. Infusion into the deep femoral artery, on the contrary, leads to no selective increased concentration in the foot. Since ordinary technique of puncturing led in 16 out of 64 time to the erroneous infusion into the deep femoral artery, after each arterial puncture the positioning of the tip of the needle has to be checked to see that it allows the drug to reach the target tissue territory directly and not after passage and dilution in the general circulation. In the case of intrafemoral infusios the correct positioning of the needle can be judged by injection of 2 ml and 5 per cent fluorescein solution.
ACCESSION #
16378121

 

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