Chow, Silas K. T.; O'Loughlin, Bernard J.
November 1961
Angiology;Nov1961, Vol. 12 Issue 11, p574
Academic Journal
This is a study of a group of 252 patients in which Ditriokon was utilized as the new contrast medium for angiocardiography and thoracic aortography. In most of the cases of this series, visualisation of cardiac chambers, great vessels and kidneys were consistently satisfactory. Clinical observation in the present study indicates that Ditriokon is a substance of low toxicity which is easily administered, affords excellent contrast, has fewer undesirable side effects, and results in a higher percentage of diagnostic films, and for this reason is considered suitable for use in angiocardiographics. This group of patients has been also studied for electrocardiographic changes immediately before, during and after selective angiocardiographies. Increase of heart rate and premature ventricular contractions were the usual findings. In coronary angiography there was greater irritability than in the angiocardiography, presumably due to a high concentration of the contrast medium reaching the brain at the same time as the coronary arteries were filling. This interpretation is suggested by the changes in the T-wave which show on the electrocardiogram and coincident systemic reactions. The site of injection is the factor which caused most of the electrocardiography abnormalities.


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