TITLE

Localization of Acid and Alkaline Phosphatase Activities in the Blood Vessels of Normotensive and Hypertensive Rats

AUTHOR(S)
Twietmeyer, T. Alan; Maynard, Jerry A.; Bhalla, Ramesh C.
PUB. DATE
May 1979
SOURCE
Angiology;May1979, Vol. 30 Issue 5, p317
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Samples of aortae and caudal arteries from normotensive and hypertensive rats were studied for cytochemical and biochemical determinations of acid and alkaline phosphatase activities. Cytochemical examination revealed an increased amount of acid phosphatase reaction product in hypertensive samples, with extensive localization to the extracellular matrix. Alkaline phosphatase activity was localized to the plasma membrane of fibroblasts and vascular Twietmeyer-Acid and Alkaline Phosphatase 325 smooth muscle cells and lo the extracellular matrix. Biochemical assays of enzyme activities supported the cytochemical findings, showing increased activity in aortae from hypertensive rats.
ACCESSION #
16373061

 

Related Articles

  • Fluoride Concentrations in Rat and Human Tooth Pulps and Their Possible Interference with Phosphatase Activities. ERICSSON, Y.; ANGMAR-M�NSSON, B. // Journal of Dental Research;Dec1983, Vol. 62 Issue 12, p1196 

    Alkaline and acid phosphatases (p-ases), fluoride (F), and calcium (Ca) were analyzed in the pulps of rat incisors and young human pre-molars. P-ase activities were about ten times higher in the rat than in the human pulps; in the latter, high p-ase activity appeared to be connected with rapid...

  • SELECTIVITY OF ENZYMES ACTIVITY BY METHIONINE. Prakash, Ram // International Journal of Pharmacology & Biological Sciences;Aug2013, Vol. 7 Issue 2, p87 

    Methionine is known to has binding sites. It makes co-valent bonds with certain molecules specially metal ions. Due to its characteristics methionine was selected to note its role to chelate cadmium ions in kidney of rat. Thus, protective effects of methionine are recorded against cadmium...

  • Effects of Aqueous Stem-Bark Extract of Momordica balsamina Linn on Some Serum Enzymes in Normal and Ethanol Fed Rats. Geidam, M. A.; Dauda, E.; Hamza, H. G. // Journal of Biological Sciences;2007, Vol. 7 Issue 2, p397 

    Aqueous stem-bark extract of Momordica balsamina Linn was administered using stomach tubes to normal and alcohol fed rats to study the effect of the extract on organs and tissues by estimating the level of some serum enzymes. The extract was administered for two weeks at a dose of 0.56 mg/100 g...

  • Methanol Extract of the Fruits of Morinda citrifolia Linn., Restores Bone Loss in Ovariectomized Rats. Shirwaikar, A.; Kamariya, Y.; Patel, B.; Nanda, S.; Parmar, V.; Khan, S. // International Journal of Pharmacology;2011, Vol. 7 Issue 4, p446 

    The objective of this study was to evaluate the effect of methanol extract of the fruits of Morinda citrifolia Linn., on osteoporosis induced by ovanectomy in female albino rats at two different dose levels of 500 and 750 mg/kg/day. Healthy female albino rats in the age group of 90 days were...

  • ROLE OF INTESTINAL ALKALINE PHOSPHATASE IN FAT TRANSPORT. Kui Chun Lam; Mistilis, Steven P. // Australian Journal of Experimental Biology & Medical Science;Jun1973, Vol. 51 Issue 3, p411 

    This article reports that marked increase in the output of intestinal alkaline phosphatase has been shown in man and animals following fatty meals. Recent studies in the rat suggested that the stimulus for intestinal alkaline phosphatase output is the uptake and transport of lipid into the...

  • Chilean crude extract of Ruta graveolens generates vasodilatation in rat aorta at cellular subtoxic concentrations. Fernández, Ignacio Jofré; Navarrete Gómez, Patricia; Parodi, Jorge; Romero Mejía, Fernando; Salvatici Salazar, Raúl // Advances in Bioscience & Biotechnology;Jan2013, Vol. 4 Issue 1, p29 

    In Chile elevated percentage of population have cardiovascular diseases, 70% of this populations is a hypertensive peoples. The Ruta graveolens (Ruta) is a medicinal plant used in different parts of the world with different therapeutics properties like dermatologic as far as anti-helmintic...

  • Vasomotion has chloride-dependency in rat mesenteric small arteries. Boedtkjer, D. M. Briggs; Matchkov, V. V.; Boedtkjer, E.; Nilsson, H.; Aalkjaer, C. // Pflugers Archiv European Journal of Physiology;Nov2008, Vol. 457 Issue 2, p389 

    The possibility that Ca2+-activated Cl− conductances (CaCCs) contribute to oscillations in vascular tone (vasomotion) is tested in isolated mesenteric small arteries from rats where cGMP independent ( I Cl(Ca)) and cGMP-dependent ( I Cl(Ca,cGMP)) chloride conductances are important. The...

  • Different biomechanical properties of medial and adventitial layers of thoracic aorta in Wistar-Kyoto and spontaneously hypertensive rats. Wei-qing HAN; Jing CHEN; Ling-yun WU; Ding-liang ZHU; Ping-jin GAO // Acta Pharmacologica Sinica;Oct2010, Vol. 31 Issue 10, p1319 

    AbstractAim:To evaluate the biomechanical properties of thoracic aorta with or without adventitia, and to determine whether there are corresponding changes with hypertension.Methods:Normotensive Wistar-Kyoto (WKY) rats and spontaneously hypertensive rats (SHR) at the age of 16 and 32 weeks were...

  • Vasodilator Action of Pentoxifylline on Microcirculation of Rat Cremaster Muscle. Sonkin, Peter L.; Long-En Chen; Seaber, Anthony V.; Hatchell, Diane L. // Angiology;Jun1992, Vol. 43 Issue 6, p462 

    Pentoxifylline improves microvascular blood flow in conditions of vascular insufficiency. The clinical benefits of pentoxifylline have been attributed to its effects on the cellular elements of whole blood, although a few studies suggest it may also be a vasodilator. The purpose of this study...

Share

Read the Article

Courtesy of VIRGINIA BEACH PUBLIC LIBRARY AND SYSTEM

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics