Measurement of Coronary Arterial Lumen by Densitometric Analysis of Angiograms

Kishon, Yehezkiel; Yerushalmi, Shmuel; Deutsch, Victor; Neufeld, Henry N.
May 1979
Angiology;May1979, Vol. 30 Issue 5, p304
Academic Journal
Densitometric curves derived from the shadow of vessels in angiogram's made by multiple photocells were used to yield the cross-sectional area curve along the lumen. The validity and accuracy of the system were tested by using vascular models with a known degree of narrowing of the lumen. The cross-sectional area curves of these tested models, as plotted by the system, revealed a degree of narrowing of the lumen which correlated well with the measured narrowing. This correlation between the values derived from the analysis of angiogram's and the values of the real measured reduction of the lumen of the vascular models was maintained when different concentrations of contrast material filled the models, and also when different degrees of narrowing were tested. It persisted when stenosis of the shadow of the vessels could not be visualized by the naked eye. Human coronary arteriogram's were similarly analyzed by this semi automated system. The cross-sectional area curves before and after the therapeutic release of arterial spasm are also presented with the tested arteriogram's. This system of measuring the coronary arterial lumen can be valuable in determining the degree and extent of coronary arterial narrowing more accurately than presently available techniques. The method can also be applied to the measurement of the lumen of other vessels.


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