Use of SQ 20881 Converting Enzyme Inhibitor in Predicting Response to Surgery in Renovascular Hypertension

Rosenthal, T.; Stern, N.; Rubinstein, Z.; Morag, B.; Adar, R.
January 1982
Angiology;Jan1982, Vol. 33 Issue 1, p11
Academic Journal
This article cites a study on the use of SQ 20881, a synthetic nonapeptide, as a prognostic tool for evaluating the potential surgical curability of renovascular hypertension. The excellent correlation number between the pre-operative response to SQ 20881 and the surgical result is extremely promising, but some caution is necessary at this stage, because the number of 5 cases is still small, and the bradykinin mechanism may play a part. It should be noted that 2 patients with definitely nonrenovascular hypertension also showed the same response pattern of lowered blood pressure.


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