Femoral Neuropathy Complicating Systemic Streptokinase Treatment for Ergotism

Ganel, A.; Zweig, A.; Adar, R.
March 1979
Angiology;Mar1979, Vol. 30 Issue 3, p192
Academic Journal
The article focuses on femoral neuropathy complicating systemic streptokinase treatment for ergotism. Bleeding of varying severity is frequent during streptokinase treatment. Streptokinase is a possible cause of femoral neuropathy, which is widely recognized as a hemorrhagic complication of hemophilia and long-term anticoagulants therapy. Streptokinase is a powerful stimulator of the fibrinolytic system used for various indications including major venous and arterial thrombosis. Several complications have been associated with streptokinase treatment, the most dangerous being bleeding from puncture, cut down or operation sites. Femoral neuropathy has been described in hemophilic patients and recently in patients on long-term anticoagulant treatment. It is caused by bleeding into the iliac and psoas muscle sheaths.


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