Carter, John P.
May 1964
Angiology;May1964, Vol. 15 Issue 5, p236
Academic Journal
In 1000 consecutive cases of thrombophlebitis, 18 instances of malignant neoplasm proved by histologic study were subsequently diagnosed. Thrombophlebitis in these cases was often of the recurrent or migratory type and was frequently resistant to anticoagulant therapy. The association was not more marked with any one type of tumor but occurred in any type of malignant visceral neoplasm. The development of thrombophlebitis did not preclude cure. Indeed, the onset of thrombophlebitis often led to recognition and treatment of the malignant visceral neoplasm. The development of thrombophlebitis may be the initial manifestation of a malignant visceral neoplasm. Search for an occult neoplasm in the patient presenting with thrombophlebitis may be quite rewarding.


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