McLean, Charles E.; Clason, W. Page C.; Stoughton, Peter V.
May 1964
Angiology;May1964, Vol. 15 Issue 5, p221
Academic Journal
One hundred six normal people were studied for variations of eight pulse pressure parameters dealing with time and pressure measurements as obtained through a left brachial artery needle. Two hundred twenty-two patients including nine separate disease states were studied in the same fashion. An increase in the mean pulse wave velocity was found in children under 10 years of age as compared with people from 10 through 39 years of age. An increase in the mean pulse wave velocity was noted in the 57 normal patients from 40 to 79 years of age when compared with the 10 to 39 age group. This increased mean velocity was identical with the mean velocity of the 0 to 9 age group. Within the limits of this study pulse wave velocity did not appear to be related to blood pressure change in hypertensive individuals. A consistent rise in mean upstroke duration (anacrotic limb time) was seen with advancing age. Total systolic mean duration was shorter for the 0 to 9 age group than for either the 10 to 39 or the 49 to 79 age group. 8. The percentage of systole used to reach the peak systolic pressure showed a progressive rise with age. 9. In resting normal people the percentage of total cycle length used for systolic contraction was remarkably constant in all age groups. The mean was 0 to 9 age group, 40 per cent; 10 to 39 age group, 39 per cent; and 40 to 79 age group, 40 per cent. 10. Within the normal range, systolic blood pressure rose consistently with age, diastolic blood pressure showed little or no change and pulse pressure as it reflected the systolic pressure, rose consistently with age. U. The analysis of six parameters of measurement, related to the contour of the brachial artery pulse pressure revealed a number of interesting observations related to aging but was of no real value for the individual patient as an aid to the diagnosis of the nine disease states studied.


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