Cuthbertson, Elizabeth M.; Gilfillan, Rutherford S.; Bachman, Ronald P.
March 1964
Angiology;Mar1964, Vol. 15 Issue 3, p145
Academic Journal
1. Mean intramedullary pressures measured in 212 bones of 95 dogs were spread over a range of 2 to 182 cm of water (1.5 to 135 mm Hg). 2. With the exception of newborn puppies, no significant variation of pressure occurred with age, sex, type of anesthesia or bone site. Pressures in the newborn were consistently low (7 to 25 cm of water), 3. Occlusion of the arterial supply to bone caused a marked decrease in pressure. Occlusion of the venous return caused an increase. Spontaneous variations in bone marrow pressure were not accompanied by simultaneous changes in arterial or venous pressure. 4. Induced changes in body temperature (35 to 41°C) caused no consistent changes in bone marrow pressure. 5. Injection of small amounts of physiological saline solution, autologous blood or plasma at cold, body or elevated temperatures, caused a sharp decrease in pressure, with a slow return to the original level. This process was not altered by denervation. 6. In dogs with ununited femoral epiphyses, injection into the epiphysis had no effect on pressure in the diaphysis (and vice versa). However, when the epiphyses were united, injection into either site influenced pressure in the other. 7. Drilling or injecting into the medullary canal appeared to cause [min in the normal or sympathectomized extremity, even when anesthesia was otherwise adequate for surgical procedures.


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