Owen, William R.; Owens, John C.; Neely, Winston B.
February 1962
Angiology;Feb1962, Vol. 13 Issue 2, p75
Academic Journal
Four to eight milligrams daily of the dextro isomer of thyroxine will lower serum cholesterol approximately 25 per cent without producing hypermetabolism. Table 4 shows other objective effects in man which may prove beneficial. While none of these assures prophylaxis or treatment of atherosclerosis, they do suggest an approach to this problem. The course of angina pectoris may be influenced favorably, although no objective appraisal of this statement is possible. The absence of significant side effects may be related to the stimulation of a physiologic excretion mechanism rather than interference with any essential process.


Related Articles

  • MEET YOUR HEART.  // O, The Oprah Magazine;Feb2011, Vol. 12 Issue 2, p120 

    The article offers information on several heart problems including blood pressure, atherosclerosis and angina pectoris.

  • THE BIOLOGIC EFFECTS OF D-THYROXINE. Tucker, Robert G. // Angiology;Feb1962, Vol. 13 Issue 2, p85 

    Is has been shown by numerous animal tests that there is a quantitative and useful separation between the biologic effects of D-thyroxine and L-thyroxine. These animal tests provide a basis for the selection of a dose of D-thyroxine in man which will decrease serum and liver cholesterol...

  • BOX 12-1 CORONARY ARTERY DISEASE. Scanlon, Valerie C.; Sanders, Tina // Essentials of Anatomy & Physiology;Jan2007, p280 

    Information on coronary artery disease from Chapter 12 of the book "Essentials of Anatomy & Physiology" is presented. It discusses the pathology of the disease and its two different types, angina and myocardial infarction. It offers information on atherosclerosis, including its risk factors and...

  • THE USE OF TRIPARANOL AND SODIUM DEXTROTHYROXINE TO LOWER SERUM CHOLESTEROL. Goyette, Edwin M.; Saad, Atif // Angiology;Feb1962, Vol. 13 Issue 2, p89 

    Triparanol in a daily dose of 250 mg lowered the serum cholesterol level in 102 of 121 patients by an average of 68 mg per cent. The average percentage drop was 19.1 per cent. Nineteen patients showed a rise which averaged 45 mg per cent, while the average percentage increase was 14 per cent....

  • atherosclerosis.  // Taber's Cyclopedic Medical Dictionary (2009);2009, Issue 21, p207 

    A definition of the medical term "atherosclerosis" is presented. It refers to the most common form of arteriosclerosis, marked by cholesterol-lipid-calcium deposits in the walls of arteries that may restrict blood flow. It discusses the pathology and treatment for the disease. Risk factors for...

  • Megakaryoblastic leukemia factor-1 gene in the susceptibility to coronary artery disease. Hinohara, Kunihiko; Nakajima, Toshiaki; Yasunami, Michio; Houda, Shigeru; Sasaoka, Taishi; Yamamoto, Ken; Bok-Soo Lee; Shibata, Hiroki; Tanaka-Takahashi, Yumiko; Takahashi, Megumi; Arimura, Takuro; Sato, Akinori; Naruse, Taeko; Jimin Ban; Inoko, Hidetoshi; Yamada, Yoshiji; Sawabe, Motoji; Park, Jeong-Euy; Izumi, Toru; Kimura, Akinori // Human Genetics;Oct2009, Vol. 126 Issue 4, p539 

    Coronary artery disease (CAD) is based on the atherosclerosis of coronary artery and may manifest with myocardial infarction or angina pectoris. Although it is widely accepted that genetic factors are linked to CAD and several disease-related genes have been reported, only a few could be...

  • Five-year follow-up of angiographic disease progression after medicine, angioplasty, or surgery. Borges, Jorge Chiquie; Lopes, Neuza; Soares, Paulo R.; Góis, Aécio F. T.; Stolf, Noedir A.; Oliveira, Sergio A.; Hueb, Whady A.; Ramires, Jose A. F. // Journal of Cardiothoracic Surgery;2010, Vol. 5, p91 

    Background: Progression of atherosclerosis in coronary artery disease is observed through consecutive angiograms. Prognosis of this progression in patients randomized to different treatments has not been established. This study compared progression of coronary artery disease in native coronary...

  • The expanding role of lipoprotein apheresis in the treatment of raised lipoprotein(a) in ischaemic heart disease and refractory angina. Khan, Tina Z.; Pottle, Alison; Pennell, Dudley J.; Barbir, Mahmoud S. // Global Cardiology Science & Practice;2014, Vol. 2014 Issue 1, p1 

    It is increasingly recognised that lipoprotein(a) [Lp(a)], an inherited, genetically-determined form of LDL-cholesterol, is an independent cardiovascular risk factor and predictor of adverse cardiovascular outcomes. Lp(a) is felt to increase cardiovascular risk via its pro-thrombotic effect and...

  • Increased Serum Leptin Concentrations in Patients with Chronic Stable Angina Pectoris and ST-Elevated Myocardial Infarction. Taneli, Fatma; Yegane, Selma; Ulman, Cevval; Tıkız, Hakan; Ali Rıza Bilge; Zeki Arı; Bekir Sami Uyanık // Angiology;May/Jun2006, Vol. 57 Issue 3, p267 

    Leptin is an adipocytokine that is produced mainly by adipose tissue; it is also identified in atherosclerotic lesions in human coronary atherosclerosis. However, the relation of serum leptin concentrations to ischemic heart disease (IHD) is still obscure. The aims of the present study were to...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics