Wexler, Bernard C.
October 1968
Angiology;Oct1968, Vol. 19 Issue 9, p554
Academic Journal
The article reports that carotid arteries manifest a particular predilection toward the development of mesenchymal or smooth muscle cell proliferation, intimal accumulation of mucopolysaccharide, medial elastolytic changes and, in advanced cases of arteriosclerosis, cartilaginous metaplasia and even bone formation. There is a sharp sex dichotomy in the development and consequences of arterial disease in that male breeder rats display minimal arteriosclerosis of the aorta but succumb in great numbers, often because of myocardial infarction.


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