Seligman, Bert
July 1968
Angiology;Jul1968, Vol. 19 Issue 7, p393
Academic Journal
Treatment of topical ulcers in 39 patents treated with Biozyme ointment or Biozyme powder was excellent. Best results were seen in ulcers caused by chronic venous insufficiency, to traumatic injury, or to varicosities. Complete healing occurred in 32 of 36 (89 per cent) such patients, many of whom had not responded to previous treatment. Direct application of Biozyme ointment or powder proved superior to application as an impregnated gauze dressing. The enzyme component of the preparation did not appear to inhibit the activity of the antibiotic nor did it interfere with normal healing. Clinically, debridement was usually complete and healing occurred at a more than satisfactory rate. In the few cases in which debridement was not complete, results were unsatisfactory and irritation was prone to develop. The results of our study reemphasize the importance of creating an environment in the ulcer which is conducive to physiologic reparative processes. Biozyme seems to be an excellent therapeutic aid in achieving this objective.


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