TITLE

BLEEDING TENDENCY OF A VASCULAR NATURE IN PATIENTS WITH MULTIPLE ALLERGIES AND HYPOGAMMAGLOBULINEMIA

AUTHOR(S)
Kupfer, Henry G.; Clark, Richard F.
PUB. DATE
July 1962
SOURCE
Angiology;Jul1962, Vol. 13 Issue 7, p303
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Case histories of a group of 20 patients are presented, in which the association among a vascular bleeding tendency, allergy and mild hypogammaglobulinemia is noted. Alteration of the peripheral vascular bed due to hypersensitivity is offered as an explanation for this hemorrhagic tendency. The inappropriate vasoconstrictor reactivity of the cutaneous vessels in atopic allergy is discussed. An abnormal cutaneous blanching phenomenon is described in the cases of this series during performance of the tourniquet test for capillary fragility. This is thought to be another manifestation of altered vascular reactivity associated with allergy.
ACCESSION #
16369976

 

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