Friedman, Sandor A.; Penneys, Raymon
October 1964
Angiology;Oct1964, Vol. 15 Issue 10, p461
Academic Journal
We determined the lactate and pyruvate concentrations of venous blood drawn from the dorsum of feet which were severely isehemic as a result of chronic arterial occlusion, in order to measure the relative amounts of anaerobic and aerobic metabolism taking place. Six patients having a blood flow capacity to their toes of less than 10 per cent of normal were compared with six normal, control subjects. No significant difference in the lactate-pyruvate ratio was found. Thus, despite severe deprivation of blood flow, no evidence of increased anaerobic metabolism in ischemic feet at rest was found.


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